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Wyniki wyszukiwania dla: brain activity
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Molecular Diagnostics of Brain Tumours by Measuring the 5-Methylcytosine Level in Their DNA
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Intra-subject class-incremental deep learning approach for EEG-based imagined speech recognition
PublikacjaBrain–computer interfaces (BCIs) aim to decode brain signals and transform them into commands for device operation. The present study aimed to decode the brain activity during imagined speech. The BCI must identify imagined words within a given vocabulary and thus perform the requested action. A possible scenario when using this approach is the gradual addition of new words to the vocabulary using incremental learning methods....
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Direct electrical stimulation of the human brain has inverse effects on the theta and gamma neural activities
PublikacjaObjective: Our goal was to analyze the electrophysiological response to direct electrical stimulation (DES) systematically applied at a wide range of parameters and anatomical sites, with particular focus on neural activities associated with memory and cognition. Methods: We used a large set of intracranial EEG (iEEG) recordings with DES from 45 subjects with electrodes...
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Assessment of Therapeutic Progress After Acquired Brain Injury Employing Electroencephalography and Autoencoder Neural Networks
PublikacjaA method developed for parametrization of EEG signals gathered from participants with acquired brain injuries is shown. Signals were recorded during therapeutic session consisting of a series of computer assisted exercises. Data acquisition was performed in a neurorehabilitation center located in Poland. The presented method may be used for comparing the performance of subjects with acquired brain injuries (ABI) who are involved...
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Brain perfusion imaging with the use of parametric modelling basing on DSC-MRI data
PublikacjaW pracy do estymacji parametrów perfuzji mózgu: przepływu krwi mózgowej (cerebral blood flow, CBF), objętości krwi mózgowej (cerebral blood volume, CBV) oraz średniego czasu przejścia (mean transit time, MTT) wykorzystano pomiary DSC-MRI (Dynamic Susceptibility Contrast Magnetic Resonance Imaging). W modelowaniu danych MRI zastoswoano model trzykompartmentowy. Przedstawiono i porównano dwa podejścia do identyfikacji modelu różniące...
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Mortality After Traumatic Brain Injury in Elderly Patients: A New Scoring System
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Myeloid-derived suppressor cells (MDSCs) in brain cancer: challenges and therapeutic strategies
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Brain-Inspired Deep Networks for Facial Expression Recognition. Frontiers in Biomedical Technologies
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Validation of the Elderly Traumatic Brain Injury Score: Observational Case Control Study
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Comparison of Three Extraction Approaches for the Isolation of Neurotransmitters from Rat Brain Samples
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Unraveling the Protective Effects of Cognitive Reserve on Cognition and Brain: A Cross-Sectional Study
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Deep brain stimulation in obsessive-compulsive disorder – case report of two patients
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Gamma oscillations precede interictal epileptiform spikes in the seizure onset zone
PublikacjaOBJECTIVE: To investigate the generation, spectral characteristics, and potential clinical significance of brain activity preceding interictal epileptiform spike discharges (IEDs) recorded with intracranial EEG. METHODS: Seventeen adult patients with drug-resistant temporal lobe epilepsy were implanted with intracranial electrodes as part of their evaluation for epilepsy surgery. IEDs detected on clinical macro- and research microelectrodes...
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Multifactor consciousness level assessment of participants with acquired brain injuries employing human–computer interfaces
PublikacjaBackground A lack of communication with people suffering from acquired brain injuries may lead to drawing erroneous conclusions regarding the diagnosis or therapy of patients. Information technology and neuroscience make it possible to enhance the diagnostic and rehabilitation process of patients with traumatic brain injury or post-hypoxia. In this paper, we present a new method for evaluation possibility of communication and the...
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Unsupervised machine-learning classification of electrophysiologically active electrodes during human cognitive task performance
PublikacjaIdentification of active electrodes that record task-relevant neurophysiological activity is needed for clinical and industrial applications as well as for investigating brain functions. We developed an unsupervised, fully automated approach to classify active electrodes showing event-related intracranial EEG (iEEG) responses from 115 patients performing a free recall verbal memory task. Our approach employed new interpretable...
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High frequency oscillations are associated with cognitive processing in human recognition memory
PublikacjaHigh frequency oscillations are associated with normal brain function, but also increasingly recognized as potential biomarkers of the epileptogenic brain. Their role in human cognition has been predominantly studied in classical gamma frequencies (30-100 Hz), which reflect neuronal network coordination involved in attention, learning and memory. Invasive brain recordings in animals and humans demonstrate that physiological oscillations...
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Carotid Artery Stenting and Blood–Brain Barrier Permeability in Subjects with Chronic Carotid Artery Stenosis
PublikacjaFailure of the blood-brain barrier (BBB) is a critical event in the development and progression of diseases such as acute ischemic stroke, chronic ischemia or small vessels disease that affect the central nervous system. It is not known whether BBB breakdown in subjects with chronic carotid artery stenosis can be restrained with postoperative recovery of cerebral perfusion. The aim of the study was to assess the short-term effect...
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Hydroxylamine attenuates the effects of simulated subarachnoid hemorrhage in the rat brain and improves neurological outcome
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Brain Fog and Quality of Life at Work in Non-Hospitalized Patients after COVID-19
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Optimized procedure of extraction, purification and proteomic analysis of nuclear proteins from mouse brain
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Comparison of protein precipitation methods for various rat brain structures prior to proteomic analysis
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Compensatory functional reorganization may precede hypertension-related brain damage and cognitive decline
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Comparison of the effectiveness of automatic EEG signal class separation algorithms
PublikacjaIn this paper, an algorithm for automatic brain activity class identification of EEG (electroencephalographic) signals is presented. EEG signals are gathered from seventeen subjects performing one of the three tasks: resting, watching a music video and playing a simple logic game. The methodology applied consists of several steps, namely: signal acquisition, signal processing utilizing z-score normalization, parametrization and...
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Human Computer Interface for Tracking Eye Movements Improves Assessment and Diagnosis of Patients With Acquired Brain Injuries
PublikacjaOne of the first clinical signs differentiating the minimally conscious state from the vegetative state is the presence of smooth pursuit eye movements occurring in direct response to moving salient stimuli. Glasgow Coma Scale (GCS) is one of the most commonly used diagnostic tools for acute phase assessment of the level of consciousness, together with a neurological examination. These classic measures are limited to qualitative...
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<p>Nanomechanics and Histopathology as Diagnostic Tools to Characterize Freshly Removed Human Brain Tumors</p>
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Sex-related patient-reported brain fog symptoms in non-hospitalised COVID-19 patients
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An automated, low-latency environment for studying the neural basis of behavior in freely moving rats
PublikacjaBackground Behavior consists of the interaction between an organism and its environment, and is controlled by the brain. Brain activity varies at sub-second time scales, but behavioral measures are usually coarse (often consisting of only binary trial outcomes). Results To overcome this mismatch, we developed the Rat Interactive Foraging Facility (RIFF): a programmable interactive arena for freely moving rats with multiple feeding...
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Serotonergic–Muscarinic Interaction within the Prefrontal Cortex as a Novel Target to Reverse Schizophrenia-Related Cognitive Symptoms
PublikacjaRecent studies revealed that the activation of serotonergic 5-HT1A and muscarinic M1, M4, or M5 receptors prevent MK-801-induced cognitive impairments in animal models. In the present study, the effectiveness of the simultaneous activation of 5-HT1A and muscarinic receptors at preventing MK-801-induced cognitive deficits in novel object recognition (NOR) or Y-maze tests was investigated. Activators of 5-HT1A (F15599), M1 (VU0357017),...
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Regional effects of amphetamine, cocaine, nomifensine and GBR 12909 on the dynamics of dopamine release and metabolism in the rat brain
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γ-Butyrolactone-sensitive and -insensitive dopamine release, and their relationship to dopamine metabolism in three rat brain regions
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Transcriptome Changes in Three Brain Regions during Chronic Lithium Administration in the Rat Models of Mania and Depression
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Evaluation of brain volume alterations in HCV-infected patients after interferon-free therapy: A pilot study
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Absence of 6-Hydroxydopamine in the Rat Brain After Treatment with Stimulants and Other Dopaminergic Agents: A Mass Fragmentographic Study
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Oral coenzyme Q 10 administration prevents the development of ischemic brain lesions in a rabbit model of symptomatic vasospasm
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Effects of melatonin on lipid peroxidation and antioxidative enzyme activities in the liver, kidneys and brain of rats administered with benzo(a)pyrene
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Modulatory Effects of Curcumin and Tyrphostins (AG494 and AG1478) on Growth Regulation and Viability of LN229 Human Brain Cancer Cells
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Antibiotic-Based Conjugates Containing Antimicrobial HLopt2 Peptide: Design, Synthesis, Antimicrobial and Cytotoxic Activities
PublikacjaRecent studies have shown that modified human lactoferrin 20−31 fragment, named HLopt2, possesses antibacterial and antifungal activity. Thus, we decided to synthesize and evaluate the biological activity of a series of conjugates based on this peptide and one of the antimicrobials with proven antibacterial (ciprofloxacin, CIP, and levofloxacin, LVX) or antifungal (fluconazole, FLC) activity. The drugs were covalently connected...
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Natural fish oil improves the differentiation and maturation of oligodendrocyte precursor cells to oligodendrocytes in vitro after interaction with the blood–brain barrier
PublikacjaThe blood–brain barrier (BBB) tightly controls the microenvironment of the central nervous system (CNS) to allow neurons to function properly. Additionally, emerging studies point to the beneficial effect of natural oils affecting a wide variety of physiological and pathological processes in the human body. In this study, using an in vitro model of the BBB, we tested the influence of natural fish oil mixture (FOM) vs. borage oil...
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Methadone is substantially less effective than morphine in modifying locomotor and brain Fos responses to subsequent methadone challenge in rats
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Predicting Outcome and Conservative Treatment Failure in Patients with Skull Fracture after Traumatic Brain Injury: A Retrospective Cohort Study
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Quantitative magnetic resonance assessment of brain atrophy related to selected aspects of disability in patients with multiple sclerosis: preliminary results
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The Impact of Common Epidemiological Factors on Gray and White Matter Volumes in Magnetic Resonance Imaging–Is Prevention of Brain Degeneration Possible?
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Independent dynamics of slow, intermediate, and fast intracranial EEG spectral activities during human memory formation
PublikacjaA wide spectrum of brain rhythms are engaged throughout the human cortex in cognitive functions. How the rhythms of various low and high frequencies are spatiotemporally coordinated across the human brain during memory processing is inconclusive. They can either be coordinated together across a wide range of the frequency spectrum or induced in specific bands. We used a large dataset of human intracranial electroencephalography...
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Neural Oscillation During Mental Imagery in Sport: An Olympic Sailor Case Study
PublikacjaThe purpose of the current study was to examine the cortical correlates of imagery depending on instructional modality (guided vs. self-produced) using various sports-related scripts. According to the expert-performance approach, we took an idiosyncratic perspective analyzing the mental imagery of an experienced two-time Olympic athlete to verify whether different instructional modalities of imagery (i.e., guided vs. self-produced)...
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Changes in oxidative stress in the rat brain during post-cardiac arrest reperfusion, and the effect of treatment with the free radical scavenger idebenone
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Changes in Gene and Protein Expression of Metalloproteinase-2 and -9 and Their Inhibitors TIMP2 and TIMP3 in Different Parts of Fluoride-Exposed Rat Brain
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Life-long norepinephrine transporter (NET) knock-out leads to the increase in the NET mRNA in brain regions rich in norepinephrine terminals
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Sleep assessment in obsessive-compulsive disorder treated with deep brain stimulation - double case report of morning and evening chronotype patients
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The serum concentration of brain-derived neurotrophic factor is lower in ambulatory and clinically stable patients with more advanced systolic heart failure
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Invasive electrophysiological patient recordings from the human brain during memory tasks with pupilometry (MC_004)
Dane BadawczeData comprise intracranial EEG (iEEG) brain activity, including electrocorticography (ECoG) signals, recorded from over 100 electrodes implanted in one patient throughout various brain regions. These iEEG signals were recorded in epilepsy patients undergoing invasive monitoring and localization of seizures when they were performing a battery of four...