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Wyniki wyszukiwania dla: cancer literacy
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Cigarette smoking and its impact on weight loss after bariatric surgery: A single center, retrospective study
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Catedral Tomada-Revista de Critica Literaria Latinoamericana-Journal of Latin American Literary Criticism
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Gold nanoparticles and their coatings, their effect on cells and their interaction with radiation
PublikacjaTwo nanometre gold nanoparticles (AuNPs), bearing sugar moieties and/or polyethylene glycolamine (PEG-amine), were synthesised and evaluated for their in vitro toxicity and ability to radiosensitise cells with 220 kV and 6 MV X-rays, using four cell lines representing normal and cancerous skin and breast tissues. In addition to the observed intrinsic cancer-selective chemotoxicity, these AuNPs acted as radiosensitisers in combination with...
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Cytotoxicity of C-2028, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst H460 cancer cells
Dane BadawczeThis study presents absorbance values of formazan product (converted from MTT) which corresponds the cytotoxicity of C-2028, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst H460 cancer cells. FA (folic acid) was used as a linker between quantum dots (QDs) and compound (C-2028) at different concentration (50-200 µM).
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Palladium versus Platinum: The Metal in the Catalytic Center of a Molecular Photocatalyst Determines the Mechanism of the Hydrogen Production with Visible Light
PublikacjaTo develop highly efficient molecular photocatalysts for visible light-driven hydrogen production, a thorough understanding of the photophysical and chemical processes in the photocatalyst is of vital importance. In this context, in situ X-ray absorption spectroscopic (XAS) investigations show that the nature of the catalytically active metal center in a (N^N)MCl2 (M=Pd or Pt) coordination sphere has a significant impact on the...
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Preliminary performance evaluation of a high resolution small animal PET scanner with monolithic crystals and depth-of-interaction encoding
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SU-GG-T-267: Imaging Properties of the OCTOPUSTM-IQ Scanner in Combination with a New Polymer Gel Dosimeter
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Adaptive Algorithm of a Tap-Changer Controller of the Power Transformer Supplying the Radial Network Reducing the Risk of Voltage Collapse
Publikacjahe development of renewable energy, including wind farms, photovoltaic farms as well as prosumer installations, and the development of electromobility pose new challenges for network operators. The results of these changes are, among others, the change of network load profiles and load flows determining greater volatility of voltages. Most of the proposed solutions do not assume a change of the transformer regulator algorithm....
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Impact of Patient- and Surgeon-Related Factors on Weight Loss after Laparoscopic Sleeve Gastrectomy—A Single-Center Study
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Canned food as a source of bisphenol a (BPA) exposure - estimation of consumption among young women from Gdansk, Poland
PublikacjaBisfenol A (BPA) jest organicznym związkiem endokrynnie czynnym , który modyfikuje pracę hormonów prowadząc do niekorzystnych dla zdrowia skutków. BPA jest substancją stabilizującą chlorek poliwinylu- jednego z najczęściej stosowanych polimerów plastików, wykorzystywanego w produkcji powszechnie używanych produktów, w tym opakowań, plastikowych butelek, zabawek, papieru paragonowego; używany jest także w produkcji żywic epoksydowych...
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A Wideband Corrugated Ridged Horn Antenna with Enhanced Gain and Stable Phase Center for X- and Ku-Band Applications
PublikacjaIn this letter, a structure and design procedure of a novel double-flared conical horn antenna with an improved gain and a stable phase center is presented. The antenna incorporates a hybrid ridged and corrugated structure. A double-ridged section is responsible for ensuring a wideband operation, whereas the corrugated section supports the hybrid mode. The antenna impedance bandwidth (VSWR < 2) is 6 GHz to 20 GHz. Excellent performance...
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Daily diet containing canned products significantly increases serum concentrations of endocrine disruptor bisphenol A in young women
PublikacjaNowadays, exposure to environmental factors is considered to be one of the possible causes of several lifestyle diseases, such as obesity, type 2 diabetes, cardiovascular disease, and cancer. Particularly noteworthy are endocrine‑disrupting chemicals (EDCs), which affect the metabolism of hormones and interact with their receptors, thus exerting adverse health effects. One of the most ubiquitous EDC in daily life is bisphenol A...
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Effect of the Catalytic Center on the Electron Transfer Dynamics in Hydrogen-Evolving Ruthenium-Based Photocatalysts Investigated by Theoretical Calculations
PublikacjaThe light-induced relaxation pathways in the molecular photocatalyst [(tbbpy)2Ru(tpphz)PtCl2]2+ are investigated with time-dependent density functional theory calculations together with the Marcus theory of electron transfer (ET). The calculations show that metal (Ru) to ligand (tpphz) charge transfer (MLCT) triplet states are populated following an excitation in the longer wavelength range of the absorption spectrum, but that an...
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ASSESSMENT OF CLIFF STABILITY AFTER THE DEMOLITION OF THE ENGINEERING FACILITIES
PublikacjaAs a part of an experiment, cliff in Gdynia Redlowo (southern coast of Baltic Sea, Gdansk Bay) was measured using terrestrial laser scanner. The main reason for taking up the subject of the Orlowo Cliff’s stability was a decision about controlled removal one of the war fortification elements. The main purpose of that analysis was to specify suitability of laser scanning in determination of slope’s stability after a violent event....
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Phuket Marine Biological Center Research Bulletin
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Journal of dance medicine & science : official publication of the International Association for Dance Medicine & Science
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Kosmos żywiołów manichejskich we wczesnej poezji Czesława Miłosza [The Cosmos of Manichaean Elements in the Early Poems of Czeslaw Milosz]
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Zwierzę, które spać nie może. Bezsenność w antropologii filozoficznej Emila Ciorana
PublikacjaThis article examines the role of insomnia in Emil Cioran’s philosophy. Taken as a whole, his work appears to be exceptionally significant both from the point of view of anthropology and illness narrative studies. There has never been any doubt that his life and work are dominated by a sense of ennui, loneliness and estrangement. Yet these themes are merely symptoms of more fundamental problems he grappled with, i.e. the grotesque...
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Sposoby zabezpieczeń rurociągów podziemnych przed wyparciem
PublikacjaCharakterystyka sposobów zabezpieczeń z zastosowaniem prefabrykowanych obciążników betonowych, płaszczy geokompozytowych z materacy Incomat i stalowych wkręcanych kotew gruntowych. Technologia wykonania oraz metodyka i przykłady obliczeń.
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Modelling Coarse Particulate Matter PM10 Concentration in the Tricity Area Using GIS
PublikacjaEnvironmental pollution is an issue of global concern, with Particulate Matter (PM) poisoning being a prime cause of lung cancer. This has led the European Commission to establish strict daily and annual PM concentration limits. The monitoring of air quality in major cities is the responsibility of European Member States. The Tricity, a 414.81 km 2 area in northern Poland, is monitored by a network of only 9 stations operated by...
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Platelet RNA Sequencing Data Through the Lens of Machine Learning
PublikacjaLiquid biopsies offer minimally invasive diagnosis and monitoring of cancer disease. This biosource is often analyzed using sequencing, which generates highly complex data that can be used using machine learning tools. Nevertheless, validating the clinical applications of such methods is challenging. It requires: (a) using data from many patients; (b) verifying potential bias concerning sample collection; and (c) adding interpretability...
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Therapeutic Potential of Carnosine and Its Derivatives in the Treatment of Human Diseases
PublikacjaDespite significant progress in the pathogenesis, diagnosis, treatment, and prevention of cancer and neurodegenerative diseases, their occurrence and mortality are still high around theworld. The resistance of cancer cells to the drugs remains a significant problem in oncology today,while in the case of neuro-degenerative diseases, therapies reversing the process are still yet to be found. Furthermore, it is important to seek new...
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Journal of Physical Education Recreation and Dance
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Agnieszka Szymik mgr
OsobyAgnieszka Szymik pracuje w Bibliotece Politechniki Gdańskiej w Sekcji Informacji Naukowo-Technicznej. Jest absolwentką informacji naukowej i bibliotekoznawstwa oraz filologii polskiej na Uniwersytecie Jagiellońskim, ukończyła także kulturoznawstwo na Uniwersytecie Gdańskim. Na studiach realizowała specjalizację zasoby cyfrowe i elektroniczne publikowanie. Na obecnym stanowisku odpowiada za zarządzanie bazami danych i zasobami elektronicznymi,...
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Design, synthesis and high antitumor potential of new unsymmetrical bisacridine derivatives towards human solid tumors, specifically pancreatic cancers and their unique ability to stabilize DNA G-quadruplexes
PublikacjaNew promising unsymmetrical bisacridine derivatives (UAs), have been developed. Three groupsincluding 36 compounds were synthesized by the condensation of 4-nitro or 4-methylacridinone, imi-dazoacridinone and triazoloacridinone derivatives with 1-nitroacridine compounds linked with anaminoalkyl chain. Cytotoxicity screening revealed the high potency of these compounds against severaltumor cell lines. Particularly, imidazoacridinone-1-nitroacridine...
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In vitro biological evaluation of a novel folic acid-targeted receptor quantum dot−β−cyclodextrin carrier for C-2028 unsymmetrical bisacridine in the treatment of human lung and prostate cancers
PublikacjaTraditional small-molecule chemotherapeutics usually do not distinguish tumors from healthy tissues. However, nanotechnology creates nanocarriers that selectively deliver drugs to their site of action. This work is the next step in the development of the quantum dot−β−cyclodextrin−folic acid (QD−β−CD−FA) platform for targeted and selected delivery of C−2028 unsymmetrical bisacridine in cancer therapy.Herein, we report an initial...
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3D point cloud as a representation of buildings: the Nanotechnology Center and the Auditorium Novum
Dane BadawczeThe product presents the point cloud in the collection of a three-dimensional database in spatial order as the representations of the Nanotechnology Center and the Auditorium Novum buildings (located on the campus of the Gdańsk University of Technology) acquired in the laser scanning technology. According to its high accuracy and precision of data acquisition...
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Centrifugal magnetic fluid seals
PublikacjaSeals perform an important and at times overlooked function in a lubricant system. They prevent or minimize the movement of the lubricant between two surfaces and also minimize the level of contamination in the system. Seals are divided into static and dynamic types. Static seals operate in systems where the mating surfaces do not move relative to each other. In contrast, dynamic seals operate under conditions where the mating surfaces...
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Modified Peptide Molecules As Potential Modulators of Shelterin Protein Functions; TRF1
PublikacjaIn this work, we present studies on relatively new and still not well-explored potential anticancer targets which are shelterin proteins, in particular the TRF1 protein can be blocked by in silico designed "peptidomimetic" molecules. TRF1 interacts directly with the TIN2 protein, and this protein-protein interaction is crucial for the proper functioning of telomere, which could be blocked by our novel modified peptide molecules....
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Indole-Acrylonitrile Derivatives as Potential Antitumor and Antimicrobial Agents—Synthesis, In Vitro and In Silico Studies
PublikacjaA series of 2-(1H-indol-2-yl)-3-acrylonitrile derivatives, 2a–x, 3, 4a–b, 5a–d, 6a–b, and 7, were synthesized as potential antitumor and antimicrobial agents. The structures of the prepared compounds were evaluated based on elemental analysis, IR, 1H- and 13NMR, as well as MS spectra. X-ray crystal analysis of the representative 2-(1H-indol-2-yl)-3-acrylonitrile 2l showed that the acrylonitrile double bond was Z-configured. All...
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LC–MS/MS analysis, antioxidant and anticholinergic properties of galanga (Alpinia officinarum Hance) rhizomes
PublikacjaGalanga (Alpinia officinarum Hance) is a pungent and aromatic rhizome, which is a member of the ginger family (Zingiberaceae). The rhizomes of this plant have been used as a traditional medicine in far east countries for relieving stomach ache, invigorating the circulatory system, treating colds, and reducing swelling. The aim of this study was to investigate antioxidant and anticholinergic properties of galanga. For this purpose,...
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CAVER Analyst 1.0: graphic tool for interactive visualization and analysis of tunnels and channels in protein structures
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STUDY IN MECHANICAL FAULT ELEMENT THERMOGRAPHY THROUGH THE MACHINE: The case of deep groove ball bearings of a career without screen.
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Pharmaceuticals and other contaminants of emerging concern in Admiralty Bay as a result of untreated wastewater discharge: Status and possible environmental consequences
PublikacjaConsidering how the impact of human activity in Antarctica is growing, the aim of this study was to conduct the first assessment of pharmaceuticals and personal care products (PPCPs), other emerging contaminants (ECs), and antibiotic resistance genes present in the western shore of the Admiralty Bay region of King George Island. In total, more than 170 substances were evaluated to assess the potential environmental risks they pose...
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Extraordinary Modernism in The Reconstruction of The City Center of Le Havre on The Example of The Church of St. Joseph According to The Design of Auguste Perret
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Coincidental Detection of Gastrointestinal Stromal Tumors During Laparoscopic Bariatric Procedures—Data and Treatment Strategy of a German Reference Center
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Administration of Inulin-Supplemented Gluten-Free Diet Modified Calcium Absorption and Caecal Microbiota in Rats in a Calcium-Dependent Manner
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Root Causes of Thin-Plate Buckling Damage at the Aft-End in Crude Oil Tanker and Verification through Buckling Analysis
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Anticancer Study on IrIII and RhIII Half-Sandwich Complexes with the Bipyridylsulfonamide Ligand
PublikacjaTwo non-platinum compounds, organometallic half-sandwich complexes [(η 5 -Cp)IrCl(L)]PF 6 (1) and [(η 5 -Cp)RhCl(L)]PF 6 (2) were prepared by treating pentamethylcyclopentadienyl chloride dimers of iridium(III) or rhodium(III) with the obtained 4-amino-N-(2,2'-bipyridin-5- yl)benzenesulfonamide ligand (L) and ammonium hexafluorophosphate. The crystal structures of ligand (L) and complexes 1 and 2 were obtained and then analyzed. Coordination...
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Automated Reasoning Based User Interface
PublikacjaMotivation: The ability to directly trace how requirements are implemented in a software system is crucial in domains that require a high level of trust (e.g. medicine, law, crisis management). This paper describes an approach that allows a high level of traceability to be achieved with model-driven engineering supported by automated reasoning. The paper gives an introduction to the novel, automated user interface synthesis in...
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DIAGNOSIS OF MALIGNANT MELANOMA BY NEURAL NETWORK ENSEMBLE-BASED SYSTEM UTILISING HAND-CRAFTED SKIN LESION FEATURES
PublikacjaMalignant melanomas are the most deadly type of skin cancer but detected early have high chances for successful treatment. In the last twenty years, the interest of automated melanoma recognition detection and classification dynamically increased partially because of public datasets appearing with dermatoscopic images of skin lesions. Automated computer-aided skin cancer detection in dermatoscopic images is a very challenging task...
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Advanced Materials Center
Kursy Online -
The mechanism of internalization study of QDgreen−CD−FA−C−2028 conjugate at IC80 value to cancer (H460, Du-145, and LNCaP) and normal (MRC-5 and PNT1A) cells
Dane BadawczeThe influence of different endocytosis inhibitors on the internalization of QDgreen−CD−FA−C−2028 conjugate at IC80 value in cancer (H460, Du-145, and LNCaP) and normal (MRC-5 and PNT1A) cells. First, the cells were preincubated with: drug-free medium (no inhibitor), at 4 °C, 5 µM Cytochalasin D, 30 µM Amiloride, 80 µM Dynasore, 25 µM Pitstop 2 and 1.5...
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Cytotoxicity of C-2028, QDgreen, QDred, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst LNCaP cancer cells
Dane BadawczeThis study presents absorbance values of formazan product (converted from MTT) which corresponds the cytotoxicity of C-2028, QDgreen, QDred, QDgreen-FA, QDred-FA, QDgreen-FA-C-2028 and QDred-FA-C-2028 aginst LNCaP cancer cells. FA (folic acid) was used as a linker between quantum dots (QDs) and compound (C-2028) at different concentration (50-200 µM).
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The Role of Inflammatory Cytokines in the Pathogenesis of Colorectal Carcinoma-Recent Findings and Review
PublikacjaThe inflammatory process plays a significant role in the development of colon cancer (CRC). Intestinal cytokine networks are critical mediators of tissue homeostasis and inflammation but also impact carcinogenesis at all stages of the disease. Recent studies suggest that inflammation is of greater importance in the serrated pathway than in the adenoma-carcinoma pathway. Interleukins have gained the most attention due to their...
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Biuro Karier - oferta dla studenta i absolwenta PG
Kursy OnlineOferta Biura Karier dla studentów i absolwentów PG z uwzględnieniem prezentacji platformy kariery Career Center (portal z ofertami pracy, praktyk, staży, aktualnymi wydarzeniami, szkoleniami, konkursami oraz bazą wiedzy).
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Translocations activating IRF4 identify a subtype of germinal center-derived B-cell lymphoma affecting predominantly children and young adults
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Radiation dose distributions in three dimensions from tomographic optical density scanning of polymer gels: I. Development of an optical scanner
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Fabrication of high-density nitrogen-vacancy (NV) center-enriched diamond particles through methyl trityl amine (C20H19N) seeding
PublikacjaDiamond particles (DPs) show promise for advanced applications in bioimaging and quantum sensing due to the presence of defect centers. This work reports a unique growth process for diamond particles composed of nitrogen-vacancy centers (NV-DPs) using a methyl trityl amine (C20H19N) diamondoid seed, which acts as a nitrogen source for NV creation. Growth was performed via microwave plasma-assisted chemical vapor deposition in a...
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A simplified method to assess the impact of ship-to-ship collision on the risk of tanker ship hull girder breaking accounting for the effect of ageing
PublikacjaOne of the most critical structural failures is the exceedance of the ship hull girder’s ultimate strength, which may result in hull breaking, and subsequent severe consequences, including loss of life and property as well as environmental damage in case of an oil spill. A cause for such loss of structural continuity can be triggered by a collision with another vessel. In addition, the ageing mechanisms of the hull structure could...