dr hab. inż. Tomasz Laskowski
Zatrudnienie
- Profesor uczelni w Katedra Technologii Leków i Biochemii
Media społecznościowe
Kontakt
- tomasz.laskowski@pg.edu.pl
Profesor uczelni
- Miejsce pracy
- Budynek B Wydziału Chemicznego
- Telefon
- +48601240161
- tomasz.laskowski@pg.edu.pl
Wybrane publikacje
-
Analytical studies on ascosin, candicidin and levorin multicomponent antifungal antibiotic complexes. The stereostructure of ascosin A2
In the class of polyene macrolides, there is a subgroup of aromatic heptaenes, which exhibit the highest antifungal activity within this type of antibiotics. Yet, due to their complex nature, aromatic heptaenes were not extensively studied and their potential as drugs is currently underexploited. Moreover, there are many inconsistencies in the literature regarding the composition and the structures of the individual components...
-
Light-Induced Transformation of the Aromatic Heptaene Antifungal Antibiotic Candicidin D into Its All-Trans Isomer
Illumination of the aromatic heptaene macrolide antifungal antibiotic candicicin D with UV light results in an isomerization of the molecule. The product formed after irradiation of the candicidin complex with UV light (λ=365nm), namely, iso-candicidin D, was isolated and subjected to 2D NMR studies, consisting of DQF-COSY, ROESY, TOCSY, HSQC, and HMBC experiments. The obtained spectral data unambiguously evidenced that iso-candicidin...
-
The Distribution of Glucosinolates in Different Phenotypes of Lepidium peruvianum and Their Role as Acetyl- and Butyrylcholinesterase Inhibitors—In Silico and In Vitro Studies
The aim of the study was to present the fingerprint of different Lepidium peruvianum tu- ber extracts showing glucosinolates-containing substances possibly playing an important role in preventinting dementia and other memory disorders. Different phenotypes of Lepidium peruvianum (Brassicaceae) tubers were analysed for their glucosinolate profile using a liquid chromatograph coupled with mass spectrometer (HPLC-ESI-QTOF-MS/MS platform)....
Uzyskane stopnie/tytuły naukowe
-
2023-12-12
Nadanie stopnia naukowego
dr hab. inż. nauki chemiczne (Dziedzina nauk ścisłych i przyrodniczych) -
2014-10-08
Nadanie stopnia naukowego
dr inż. Biotechnologia - nauki chemiczne (Dziedzina nauk chemicznych)
wyświetlono 2766 razy