Year 2020

• Aerobic Cytotoxicity of Aromatic N-Oxides: The Role of NAD(P)H:Quinone Oxidoreductase (NQO1)

  Publication

  • A. Nemeikaitė-Čėnienė
  • J. Šarlauskas
  • L. Misevičienė
  • A. Marozienė
  • V. Jonušienė
  • M. Lesanavičius
  • N. Čėnas
  • J. Sarlauskas

  - International Journal of Molecular Sciences - Year 2020

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• Preliminary Investigation of the Antibacterial Activity of Antitumor Drug 3-Amino-1,2,4-Benzotriazine-1,4-Dioxide (Tirapazamine) and its Derivatives

  Publication

  • E. Polmickaitė-Smirnova
  • J. Šarlauskas
  • K. Krikštopaitis
  • Ž. Lukšienė
  • Z. Staniulytė
  • Ž. Anusevičius
  • J. Sarlauskas

  - Applied Sciences-Basel - Year 2020

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• Reactions of Plasmodium falciparum Ferredoxin:NADP+ Oxidoreductase with Redox Cycling Xenobiotics: A Mechanistic Study

  Publication

  • M. Lesanavičius
  • A. Aliverti
  • J. Šarlauskas
  • N. Čėnas
  • J. Sarlauskas

  - International Journal of Molecular Sciences - Year 2020

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Year 2019

• Antiplasmodial Activity of Nitroaromatic Compounds: Correlation with Their Reduction Potential and Inhibitory Action on Plasmodium falciparum Glutathione Reductase

  Publication

  • A. Marozienė
  • M. Lesanavičius
  • E. Davioud-Charvet
  • A. Aliverti
  • P. Grellier
  • J. Šarlauskas
  • N. Čėnas
  • J. Sarlauskas

  - MOLECULES - Year 2019

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• Kinetics of Flavoenzyme-Catalyzed Reduction of Tirapazamine Derivatives: Implications for Their Prooxidant Cytotoxicity

  Publication

  • . Nemeikaitė-Čėnienė
  • . Šarlauskas
  • . Jonušienė
  • . Marozienė
  • . Misevičienė
  • . Yantsevich
  • . Čėnas
  • J. Sarlauskas

  - International Journal of Molecular Sciences - Year 2019

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Year 2016

• Identification of Novel Chemical Scaffolds Inhibiting Trypanothione Synthetase from Pathogenic Trypanosomatids

  Publication

  • D. Benítez
  • A. Medeiros
  • L. Fiestas
  • E. Panozzo-Zenere
  • F. Maiwald
  • K. Prousis
  • M. Roussaki
  • T. Calogeropoulou
  • A. Detsi
  • T. Jaeger... and 7 others

  - PLOS Neglected Tropical Diseases - Year 2016

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• Naphtho[1′,2′:4,5]imidazo[1,2-a]pyridine-5,6-diones: Synthesis, enzymatic reduction and cytotoxic activity

  Publication

  • J. Šarlauskas
  • M. Pečiukaitytė-Alksnė
  • L. Misevičienė
  • A. Marozienė
  • E. Polmickaitė
  • Z. Staniulytė
  • N. Čėnas
  • Ž. Anusevičius
  • J. Sarlauskas

  - Bioorganic & Medicinal Chemistry Letters - Year 2016

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• Quantitative proteomic analysis of anticancer drug RH1 resistance in liver carcinoma

  Publication

  • M. Ger
  • A. Kaupinis
  • A. Nemeikaite-Ceniene
  • J. Sarlauskas
  • J. Cicenas
  • N. Cenas
  • M. Valius

  - Biochimica et Biophysica Acta (BBA) - Proteins and Proteomics - Year 2016

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• Study of Bioreductive Anticancer Agent RH-1-Induced Signals Leading the Wild-Type p53-Bearing Lung Cancer A549 Cells to Apoptosis

  Publication

  • A. Stulpinas
  • A. Imbrasaitė
  • N. Krestnikova
  • J. Šarlauskas
  • N. Čėnas
  • A. Kalvelytė
  • J. Sarlauskas

  - CHEMICAL RESEARCH IN TOXICOLOGY - Year 2016

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Year 2014

• The Study of NADPH-Dependent Flavoenzyme-Catalyzed Reduction of Benzo[1,2-c]1,2,5-oxadiazole N-Oxides (Benzofuroxans)

  Publication

  • J. Šarlauskas
  • L. Misevičienė
  • A. Marozienė
  • L. Karvelis
  • J. Stankevičiūtė
  • K. Krikštopaitis
  • N. Čėnas
  • A. Yantsevich
  • A. Laurynėnas
  • Ž. Anusevičius
  • J. Sarlauskas

  - International Journal of Molecular Sciences - Year 2014

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Year 2012

• Quinone- and nitroreductase reactions of Thermotoga maritima peroxiredoxin–nitroreductase hybrid enzyme

  Publication

  • Ž. Anusevičius
  • L. Misevičienė
  • J. Šarlauskas
  • N. Rouhier
  • J. Jacquot
  • N. Čėnas
  • J. Sarlauskas

  - Archives of Biochemistry and Biophysics - Year 2012

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Year 2011

• Redox reactions of the FAD-containing apoptosis-inducing factor (AIF) with quinoidal xenobiotics: A mechanistic study

  Publication

  • L. Misevičienė
  • Ž. Anusevičius
  • J. Šarlauskas
  • I. Sevrioukova
  • N. Čėnas
  • J. Sarlauskas

  - Archives of Biochemistry and Biophysics - Year 2011

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Year 2010

• Antiplasmodial activity of quinones: Roles of aziridinyl substituents and the inhibition of Plasmodium falciparum glutathione reductase

  Publication

  • P. Grellier
  • A. Marozienė
  • H. Nivinskas
  • J. Šarlauskas
  • A. Aliverti
  • N. Čėnas
  • J. Sarlauskas

  - Archives of Biochemistry and Biophysics - Year 2010

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Year 2008

• Reduction of aliphatic nitroesters and N-nitramines by Enterobacter cloacae PB2 pentaerythritol tetranitrate reductase

  Publication

  • H. Nivinskas
  • J. Šarlauskas
  • Ž. Anusevičius
  • H. Toogood
  • N. Scrutton
  • N. Čėnas
  • J. Sarlauskas

  - FEBS Journal - Year 2008

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Year 2006

• Interactions of Nitroaromatic Compounds with the Mammalian Selenoprotein Thioredoxin Reductase and the Relation to Induction of Apoptosis in Human Cancer Cells

  Publication

  • N. Cenas
  • S. Prast
  • H. Nivinskas
  • J. Sarlauskas
  • E. Arnér

  - Journal of Biological Chemistry - Year 2006

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Year 2004

• Flavoenzyme-catalyzed redox cycling of hydroxylamino- and amino metabolites of 2,4,6-trinitrotoluene: implications for their cytotoxicity

  Publication

  • J. Šarlauskas
  • A. Nemeikaite-Č≐niene
  • Ž. Anusevičius
  • L. Misevičien≐
  • M. Julvez
  • M. Medina
  • C. Gomez-Moreno
  • N. Č≐nas
  • J. Sarlauskas

  - Archives of Biochemistry and Biophysics - Year 2004

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• Interactions of Quinones with Thioredoxin Reductase

  Publication

  • N. Cenas
  • H. Nivinskas
  • Z. Anusevicius
  • J. Sarlauskas
  • F. Lederer
  • E. Arnér

  - Journal of Biological Chemistry - Year 2004

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• Structure-Activity Relationships in Two-Electron Reduction of Quinones

  Publication

  • N. Č≐nas
  • Ž. Anusevičius
  • H. Nivinskas
  • L. Misevičien≐
  • J. Šarlauskas
  • J. Sarlauskas

  - Year 2004

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Year 2003

• Cytotoxicity of RH1 and related aziridinylbenzoquinones: involvement of activation by NAD(P)H:quinone oxidoreductase (NQO1) and oxidative stress

  Publication

  • A. Nemeikait≐-Č≐niene
  • J. Šarlauskas
  • Ž. Anusevičius
  • H. Nivinskas
  • N. Č≐nas
  • J. Sarlauskas

  - Archives of Biochemistry and Biophysics - Year 2003

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Year 2002

• Two-electron reduction of quinones by Enterobacter cloacae NAD(P)H:nitroreductase: quantitative structure-activity relationships

  Publication

  • H. Nivinskas
  • S. Staškevičien≐
  • J. Šarlauskas
  • R. Koder
  • A. Miller
  • N. Č≐nas
  • J. Sarlauskas

  - Archives of Biochemistry and Biophysics - Year 2002

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• Two-electron reduction of quinones by rat liver NAD(P)H:quinone oxidoreductase: quantitative structure–activity relationships

  Publication

  • Ž. Anusevičius
  • J. Šarlauskas
  • N. Č≐nas
  • J. Sarlauskas

  - Archives of Biochemistry and Biophysics - Year 2002

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Year 2001

• Antiplasmodial Activity of Nitroaromatic and Quinoidal Compounds: Redox Potential vs Inhibition of Erythrocyte Glutathione Reductase

  Publication

  • P. Grellier
  • J. Šarlauskas
  • Ž. Anusevičius
  • A. Marozien≐
  • C. Houee-Levin
  • J. Schrevel
  • N. Č≐nas
  • J. Sarlauskas

  - Archives of Biochemistry and Biophysics - Year 2001

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• Quantitative structure–activity relationships in enzymatic single-electron reduction of nitroaromatic explosives: implications for their cytotoxicity

  Publication

  • N. Č≐nas
  • A. Nemeikait≐-Č≐nien≐
  • E. Sergedien≐
  • H. Nivinskas
  • Ž. Anusevičius
  • J. Šarlauskas
  • J. Sarlauskas

  - BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS - Year 2001

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• Quantitative Structure–Activity Relationships in Two-Electron Reduction of Nitroaromatic Compounds by Enterobacter cloacae NAD(P)H:Nitroreductase

  Publication

  • H. Nivinskas
  • R. Koder
  • Ž. Anusevičius
  • J. Šarlauskas
  • A. Miller
  • N. Č≐nas
  • J. Sarlauskas

  - Archives of Biochemistry and Biophysics - Year 2001

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Year 2000

• Inhibition of phthalocyanine-sensitized photohemolysis of human erythrocytes by polyphenolic antioxidants: description of quantitative structure–activity relationships

  Publication

  • A. Maroziene
  • J. Sarlauskas

  - Cancer Letters - Year 2000

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Year 1999

• Quantitative structure activity relationships for the electron transfer reactions ofAnabaenaPCC 7119 ferredoxin-NADP+oxidoreductase with nitrobenzene and nitrobenzimidazolone derivatives: mechanistic implications

  Publication

  • Z. Anusevicius
  • A. Soffers
  • N. Cenas
  • J. Sarlauskas
  • M. Martinez-Julvez
  • I. Rietjens

  - FEBS Letters - Year 1999

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Year 1998

• DT-diaphorase catalyzes N-denitration and redox cycling of tetryl

  Publication

  • Ž. Anusevičius
  • J. Šarlauskas
  • H. Nivinskas
  • J. Segura-Aguilar
  • N. Č≐nas
  • J. Sarlauskas

  - FEBS Letters - Year 1998

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• Nitroreductase reactions of Arabidopsis thaliana thioredoxin reductase

  Publication

  • V. Miškinien≐
  • J. Šarlauskas
  • J. Jacquot
  • N. Č≐nas
  • J. Sarlauskas

  - Biochimica et Biophysica Acta (BBA) - Bioenergetics - Year 1998

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• Quantitative structure activity relationships for the conversion of nitrobenzimidazolones and nitrobenzimidazoles by DT-diaphorase: implications for the kinetic mechanism

  Publication

  • Z. Anusevicius
  • A. Soffers
  • N. Cénas
  • J. Sarlauskas
  • J. Segura-Aguilar
  • I. Rietjens

  - FEBS Letters - Year 1998

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Year 1997

• Nitrobenzimidazoles as Substrates for DT-Diaphorase and Redox Cycling Compounds: Their Enzymatic Reactions and Cytotoxicity

  Publication

  • J. šarlauskas
  • E. Dičkancait≐
  • A. Nemeikait≐
  • Ž. Anusevičius
  • H. Nivinskas
  • J. Segura-Aguilar
  • N. č≐nas
  • J. Sarlauskas

  - Archives of Biochemistry and Biophysics - Year 1997

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Year 1994

• Chinifur, a Selective Inhibitor and "Subversive Substrate" for Trypanosoma congolense Trypanothione Reductase

  Publication

  • N. Cenas
  • D. Bironaite
  • E. Dickancaite
  • Z. Anusevicius
  • J. Sarlauskas
  • J. Blanchard
  • J. Sarlauskas

  - BIOCHEMICAL AND BIOPHYSICAL RESEARCH COMMUNICATIONS - Year 1994

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