Hepatic fibrosis - Male, 53 - Tissue image [5250730010645741] - Open Research Data - Bridge of Knowledge

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Hepatic fibrosis - Male, 53 - Tissue image [5250730010645741]

Description

This is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

The detailed information about the patient, sample, and diagnosis are as follows:

Patient:

Age: 53

Clinical description: Liver fibrosis. Congenital haemochromatosis.

Gender: Male

Diagnosis:

Classification: ICD-10_10-20

Classification code: Chapter XI - Diseases of the digestive system

Diagnosis: Hepatic fibrosis

Result of the histopathological examination: In the examined oligopyoptate (one partially fragmented section) fragments of the enlarged biliary spaces are usually present, containing a large number of inflammatory cells, mainly mononuclear. Within the above-mentioned enlarged spaces, there are features of pronounced fibrogenesis, characterized by intense portal and periportal fibrosis with the formation of portal-portal fibrous bridges, it is possible that also portal-central, with the presence of a single regenerative nodule. In some portal spaces accumulating elements of collagen connective tissue, there is a clear proliferation of bile ducts. Large groups of enlarged hepatocytes are observed, especially those located near the portal spaces, depositing iron in the form of haemosiderin, and stimulated Borowicz-Kupffer cells accumulating hemosiderin. In places, there are features of mixed steatosis of quite numerous hepatocytes, with a predominance of large droplets. The microscopic image of the examined material indicates the process of intense fibrosis of on the base of congenital haemochromatosis, although coexistence of another liver pathology cannot be ruled out.

Sample:

Material: FFPE

Collecting method: Surgical specimen

Topography: DIGESTIVE ORGANS

Organ: LIVER AND INTRAHEPATIC BILE DUCTS

Tissue: Liver

Type of staining: positive/HC

Staining: Sirius Red

Antibody: Not applicable

Technology:

Equipment: Pannoramic 250 3DHistech

Lens: 20x

Organization:

Source: Medical University Gdańsk

Dataset file

4ab1bc8d-71eb-4cc8-91e3-df4e4a73a79c
1.9 GB, S3 ETag , downloads: 21
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File details

License:
Creative Commons: by-nc-sa 4.0 open in new tab
CC BY-NC-SA
Non-commercial - Share-alike
Raw data:
Data contained in dataset was not processed.
Software:
CaseViewer 2.3

Details

Year of publication:
2022
Verification date:
2022-05-10
Creation date:
2022
Dataset language:
English
Fields of science:
  • medical sciences (Medical and Health Sciences )
DOI:
DOI ID 10.34808/24ft-8815 open in new tab
Ethical papers:
NKBBN/421-306/2020
Verified by:
Medical University of Gdańsk

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