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Description
The data set contains live-cell imaging of A549 and H460 cells' mitochondria after exposure to TXT2 and TXT4. Cells were exposed for 6 h to the tested compounds at their IC90 concentration or to DMSO. Then, mitochondrial labelling was performed by incubating the cells with a MitoTracker Green FM probe (Thermo Fisher Scientific) and Hoechst 33342 (Thermo Fisher Scientific). Images were acquired with an LSM 800 inverted laser scanning confocal microscope (Carl Zeiss, Jena, German), equipped with an Airyscan detector for high-resolution confocal scanning using a ×63 1.4 NA Plan Apochromat objective (Carl Zeiss). Cells were incubated in an incubation chamber at 37°C with 5% CO2.
Dataset file
Microscopy analysis of A549 and H460 cells' mitochondria after exposure to TXT2 and TXT4.zip
7.8 MB,
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c38d8212a71837364585c9d14781d06e-1,
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File details
- License:
-
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CC BY-NC-SANon-commercial - Share-alike - Raw data:
- Data contained in dataset was not processed.
Details
- Year of publication:
- 2022
- Verification date:
- 2023-03-24
- Dataset language:
- English
- Fields of science:
-
- biological sciences (Natural sciences)
- DOI:
- DOI ID 10.34808/69c8-7w23 open in new tab
- Funding:
- Verified by:
- Gdańsk University of Technology
Keywords
References
- publication Teloxantron inhibits the processivity of telomerase with preferential DNA damage on telomeres
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