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prof. dr hab. Paweł Wiczling
Employment
- 2003 - present at Department of Biopharmaceutics and Pharmacodynamics
Publications
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total: 62
Catalog Publications
Year 2021
Year 2020
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Nonstationary Pharmacokinetics of Caspofungin in ICU Patients
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Population analysis to assess the influence of age and body weight on pharmacokinetics and pharmacodynamics of dexmedetomidine in New Zealand White rabbits
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Population Pharmacokinetic Model of Dexmedetomidine in a Heterogeneous Group of Patients
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Population pharmacokinetics of standard-dose meropenem in critically ill patients on continuous renal replacement therapy: a prospective observational trial
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Proof-of-concept study on improved efficacy of rHuEPO administered as a long-term infusion in rats
Publication
Year 2019
Year 2018
Year 2017
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Age-structured population model of cell survival
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Flip-Flop Phenomenon in Epidural Sufentanil Pharmacokinetics: A Population Study in Children and Infants
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HPLC–MS/MS method for dexmedetomidine quantification with Design of Experiments approach: application to pediatric pharmacokinetic study
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Multilevel pharmacokinetics-driven modeling of metabolomics data
Publication
Year 2016
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How Much Can We Learn from a Single Chromatographic Experiment? A Bayesian Perspective
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Pharmacokinetics and bioequivalence of a liquid formulation of hydroxyurea in children with sickle cell anemia
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Pharmacokinetics and pharmacodynamics of propofol and fentanyl in patients undergoing abdominal aortic surgery - a study of pharmacodynamic drug-drug interactions
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Pharmacokinetics of sufentanil during long-term infusion in critically ill pediatric patients
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Quantitative structure-(chromatographic) retention relationship models for dissociating compounds
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The pharmacokinetics of dexmedetomidine during long-term infusion in critically ill pediatric patients. A Bayesian approach with informative priors
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The pharmacokinetics of propofol in ICU patients undergoing long-term sedation
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Ultra-high performance liquid chromatographic determination of levofloxacin in human plasma and prostate tissue with use of experimental design optimization procedures
Publication
Year 2015
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Least absolute shrinkage and selection operator and dimensionality reduction techniques in quantitative structure retention relationship modeling of retention in hydrophilic interaction liquid chromatography
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Maximum A Posteriori Bayesian Estimation of Chromatographic Parameters by Limited Number of Experiments
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Melatonin and clonidine premedication has similar impact on the pharmacokinetics and pharmacodynamics of propofol target controlled-infusions
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Pharmacokinetics and pharmacodynamics of propofol in cancer patients undergoing major lung surgery
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Simultaneous determination of hydrophobicity and dissociation constant for a large set of compounds by gradient reverse phase high performance liquid chromatography–mass spectrometry technique
Publication
Year 2014
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Development and validation of UHPLC method for the determination of cyclosporine A in biological samples
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Pharmacokinetics and pharmacodynamics of propofol in children undergoing different types of surgeries
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Population pharmacokinetics of hydroxyurea for children and adolescents with sickle cell disease
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The influence of the time of day on midazolam pharmacokinetics and pharmacodynamics in rabbits
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The quantification of reticulocyte maturation and neocytolysis in normal and erythropoietin stimulated rats
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The simultaneous determination of hydrophobicity and dissociation constant by liquid chromatography–mass spectrometry
Publication
Year 2013
Year 2012
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A new pH/organic modifier gradient RP HPLC method for convenient determination of lipophilicity and acidity of drugs as applied to established imidazoline agents
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New supervised alignment method as a preprocessing tool for chromatographic data in metabolomic studies
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Pharmacokinetics and pharmacodynamics of propofol in patients undergoing abdominal aortic surgery
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Potential pitfalls of propofol target controlled infusion delivery related to its pharmacokinetics and pharmacodynamics
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QSAR, QSPR and QSRR in Terms of 3-D-MoRSE Descriptors for In Silico Screening of Clofibric Acid Analogues
Publication
Year 2011
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Gradient reversed-phase high-performance chromatography of ionogenic analytes
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Influence of Time of Day on Propofol Pharmacokinetics and Pharmacodynamics in Rabbits
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Reversed-Phase TLC and HPLC Retention Data in Correlation Studies with in Silico Molecular Descriptors and Druglikeness Properties of Newly Synthesized Anticonvulsant Succinimide Derivatives
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Thermodynamic vs. extrathermodynamic modeling of chromatographic retention
Publication
Year 2010
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Assessing circadian rhythms in propofol PK and PD during prolonged infusion in ICU patients
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pH Gradient as a Tool for the Separation of Ionizable Analytes in Reversed-Phase High-Performance Chromatography
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Pharmacokinetics and Antibody Responses to the CD3 Antibody Otelixizumab Used in the Treatment of Type 1 Diabetes
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Pharmacokinetics and Pharmacodynamics of a Chimeric/Humanized Anti-CD3 Monoclonal Antibody, Otelixizumab (TRX4), in Subjects With Psoriasis and With Type 1 Diabetes Mellitus
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Population Modeling of Filgrastim PK-PD in Healthy Adults Following Intravenous and Subcutaneous Administrations
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Retention time and peak width in the combined pH/organic modifier gradient high performance liquid chromatography
Publication
Year 2009
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Flow cytometric analysis of reticulocyte maturation after erythropoietin administration in rats
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Population Pharmacokinetic Modelling of Filgrastim in Healthy Adults following Intravenous and Subcutaneous Administrations
Publication
Year 2008
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