Search results for: DNA NANOTECHNOLOGY

• Evaluating experimental molecular physics studies of radiation damage in DNA*

  Publication

  • M. Śmiałek-Telega

  - EUROPEAN PHYSICAL JOURNAL D - Year 2016

  The field of Atomic and Molecular Physics (AMP) is a mature field exploring the spectroscopy, excitation, ionisation of atoms and molecules in all three phases. Understanding of the spectroscopy and collisional dynamics of AMP has been fundamental to the development and application of quantum mechanics and is applied across a broad range of disparate disciplines including atmospheric sciences, astrochemistry, combustion and environmental...

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• Folding‐upon‐repair DNA nanoswitches for monitoring DNA repair enzymes activity

  Publication

  • N. Farag
  • R. Mattossovich
  • R. Merlo
  • Ł. Nierzwicki
  • G. Palermo
  • A. Porchetta
  • G. Perugino
  • F. Ricci

  - ANGEWANDTE CHEMIE-INTERNATIONAL EDITION - Year 2021

  We demonstrate here a new class of DNA‐based nanoswitches that, upon enzymatic repair, could undergo a conformational change mechanism leading to a change in fluorescent signal. Such folding‐upon‐repair DNA nanoswitches are synthetic DNA sequences containing O6‐methyl‐guanine (O6‐MeG) nucleobases and labelled with a fluorophore/quencher optical pair. The nanoswitches are rationally designed so that only upon enzymatic demethylation...

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