Search results for: IMMUNOPEPTIDOME

• Cancer immune escape: the role of antigen presentation machinery

  Publication

  • A. Kallingal
  • M. Olszewski
  • N. Maciejewska
  • W. Brankiewicz
  • M. Bagiński

  - JOURNAL OF CANCER RESEARCH AND CLINICAL ONCOLOGY - Year 2023

  The mechanisms of antigen processing and presentation play a crucial role in the recognition and targeting of cancer cells by the immune system. Cancer cells can evade the immune system by downregulating or losing the expression of the proteins recognized by the immune cells as antigens, creating an immunosuppressive microenvironment, and altering their ability to process and present antigens. This review focuses on the mechanisms...

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