Search results for: MATRIX METALLOPROTEINASES

• Kallikrein-Related Peptidase 14 Activates Zymogens of Membrane Type Matrix Metalloproteinases (MT-MMPs)—A CleavEx Based Analysis

  Publication

  • K. Falkowski
  • E. Bielecka
  • I. Thøgersen
  • O. Bocheńska
  • K. Płaza
  • M. Kalińska
  • L. Sąsiadek
  • M. Magoch
  • A. Pęcak
  • M. Wiśniewska... and 16 others

  - International Journal of Molecular Sciences - Year 2020

  Full text to download in external service

• Kallikrein-related peptidase 14 activates zymogens of membrane type matrix metalloproteinases (MT-MMPs) - a CleavEx library-based analysis

  Publication

  • K. Falkowski
  • E. Bielecka
  • I. Thøgersen
  • O. Bocheńska
  • K. Płaza
  • M. Kalińska
  • L. Sąsiadek
  • M. Magoch
  • A. Pęcak
  • M. Wiśniewska... and 16 others

  - Year 2020

  Full text to download in external service

• The Product of Matrix Metalloproteinase Cleavage of Doxorubicin Conjugate for Anticancer Drug Delivery: Calorimetric, Spectroscopic, and Molecular Dynamics Studies on Peptide–Doxorubicin Binding to DNA

  Publication

  • K. Butowska
  • K. Żamojć
  • M. Kogut
  • W. Kozak
  • D. Wyrzykowski
  • W. Wiczk
  • J. Czub
  • J. Piosik
  • J. Rak

  - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2020

  Matrix metalloproteinases (MMPs) are extracellular matrix degradation factors, promoting cancer progression. Hence, they could provide an enzyme-assisted delivery of doxorubicin (DOX) in cancer treatment. In the current study, the intercalation process of DOX and tetrapeptide-DOX, the product of the MMPs' cleavage of carrier-linked DOX, into dsDNA was investigated using stationary and time-resolved fluorescence spectroscopy, UV-Vis...

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