Search results for: MET-ENKEPHALIN

• Opioid Growth Factor and its Derivatives as Potential Non-toxic Multifunctional Anticancer and Analgesic Compounds

  Publication

  • J. Budka
  • S. Kowalski
  • M. Chylińska
  • K. Dzierzbicka
  • I. Inkielewicz-Stępniak

  - CURRENT MEDICINAL CHEMISTRY - Year 2021

  In this paper, we review the structure-activity relationship of OGF and its analogues. We highlight also OGF derivatives with analgesic, immunomodulatory activity and the ability to penetrate the blood-brain barrier and may be used as safe agents enhancing chemotherapy efficacy and improving quality of life in cancer patients. The reviewed papers indicate that Met-enkephalin and its analogues are interesting candidates for the...

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