Search results for: PROTACS

• HDAC Inhibitors: Innovative Strategies for Their Design and Applications

  Publication

  • M. Daśko
  • B. De Pascual-Teresa
  • I. Ortín
  • A. Ramos

  - MOLECULES - Year 2022

  Histone deacetylases (HDACs) are a large family of epigenetic metalloenzymes that are involved in gene transcription and regulation, cell proliferation, differentiation, migration, and death, as well as angiogenesis. Particularly, disorders of the HDACs expression are linked to the development of many types of cancer and neurodegenerative diseases, making them interesting molecular targets for the design of new efficient drugs...

  Full text available to download