Search results for: RNASEQ

• Utilizing Genome-Wide mRNA Profiling to Identify the Cytotoxic Chemotherapeutic Mechanism of Triazoloacridone C-1305 as Direct Microtubule Stabilization

  Publication

  • J. Króliczewski,
  • S. Bartoszewska
  • M. Dudkowska
  • D. Janiszewska
  • A. Biernatowska
  • D. Crossman
  • K. Krzymiński
  • M. Wysocka
  • A. Romanowska
  • M. Bagiński... and 6 others

  - Cancers - Year 2020

  Rational drug design and in vitro pharmacology profiling constitute the gold standard in drug development pipelines. Problems arise, however, because this process is often dicult due to limited information regarding the complete identification of a molecule’s biological activities. The increasing aordability of genome-wide next-generation technologies now provides an excellent opportunity to understand a compound’s diverse eects...

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