Search results for: TPEF

• In vivo imaging of the human eye using a two-photon excited fluorescence scanning laser ophthalmoscope

  Publication

  • J. Boguslawski
  • G. Palczewska
  • S. Tomczewski
  • J. Milkiewicz
  • P. Kasprzycki
  • D. Stachowiak
  • K. Komar
  • M. J. Marzejon
  • B. L. Sikorski
  • A. Hudzikowski... and 6 others

  - JOURNAL OF CLINICAL INVESTIGATION - Year 2022

  BACKGROUND. Noninvasive assessment of metabolic processes that sustain regeneration of human retinal visual pigments (visual cycle) is essential to improve ophthalmic diagnostics and to accelerate development of new treatments to counter retinal diseases. Fluorescent vitamin A derivatives, which are the chemical intermediates of these processes, are highly sensitive to UV light; thus, safe analyses of these processes in humans...

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