Search results for: amikacin encapsulation

• Encapsulation of Amikacin into Microparticles Based on Low-Molecular-Weight Poly(lactic acid) and Poly(lactic acid-co-polyethylene glycol)

  Publication

  • M. Glinka
  • K. Filatova
  • J. Kucińska-Lipka
  • E. D. Bergerova
  • A. Wasik
  • V. Sedlařík

  - MOLECULAR PHARMACEUTICS - Year 2021

  The aim of this study was to fabricate novel microparticles (MPs) for efficient and long-term delivery of amikacin (AMI). The emulsification method proposed for encapsulating AMI employed low-molecular-weight poly(lactic acid) (PLA) and poly(lactic acid-co-polyethylene glycol) (PLA−PEG), both supplemented with poly(vinyl alcohol) (PVA). The diameters of the particles obtained were determined as less than 30 μm. Based on an in-vitro...

  Full text available to download