Search results for: beta-peptoid

• Hybrid analogues of SFTI-1 modified in P1 position by β- and γ-amino acids and N-substituted β-alanines

  Publication

  • D. Debowski
  • R. Łukajtis
  • M. Filipowicz
  • P. Strzelecka
  • M. Wysocka
  • A. Łęgowska
  • A. Lesner
  • K. Rolka
  • A. Lesner

  - BIOPOLYMERS - Year 2013

  A series of compounds containing either non-proteinogenic beta-/gamma-amino acids or N-substituted beta-alanine residues (beta-peptoid units) in P-1 specificity position were synthesized based on the structure of sunflower trypsin inhibitor 1 (SFTI-1). The compounds were synthesized on a solid support; the N-substituted beta-alanines (beta Nhlys and beta Nhphe) were introduced into a peptidomimetic chain via a two-step approach...

  Full text to download in external service