Search results for: spike glycoprotein

• Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site

  Publication

  • U. Kalathiya
  • M. Padariya
  • M. Mayordomo
  • M. Lisowska
  • J. Nicholson
  • A. Singh
  • M. Bagiński
  • R. Fahraeus
  • N. Carragher
  • K. Ball... and 4 others

  - Journal of Clinical Medicine - Year 2020

  An important stage in severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) life cycle is the binding of the spike (S) protein to the angiotensin converting enzyme-2 (ACE2) host cell receptor. Therefore, to explore conserved features in spike protein dynamics and to identify potentially novel regions for drugging, we measured spike protein variability derived from 791 viral genomes and studied its properties by molecular...

  Full text available to download

• Highly Conserved Homotrimer Cavity Formed by the SARS-CoV-2 Spike Glycoprotein: A Novel Binding Site

  Publication

  • U. Kalathiya
  • M. Padariya
  • M. Mayordomo
  • M. Lisowska
  • J. Nicholson
  • A. Singh
  • M. Baginski
  • R. Fåhraeus
  • N. Carragher
  • K. Ball... and 4 others

  - Year 2020

  Full text to download in external service