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Search results for: survivin
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Nicotinamide phosphorybosiltransferase overexpression in thyroid malignancies and its correlation with tumor stage and with survivin/survivin DEx3 expression
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Survivin splice variants expression in thyroid malignancy
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Evaluation of survivin splice variants in pituitary tumors
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Survivin Delta Ex3 Overexpression in Thyroid Malignancies
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Survivin DEx3 as a biomarker of thyroid cancers: A study at the mRNA and protein level
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Survivin expression in invasive pituitary gland adenomas with a diameter exceeding 20 mm
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Prognostic significance of pretreatment VEGF, survivin, and Smac/DIABLO serum levels in patients with serous ovarian carcinoma
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Are Radiosensitive and Regular Response Cells Homogeneous in Their Correlations Between Copy Number State and Surviving Fraction After Irradiation?
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Targeting of FLT3-ITD kinase contributes to high selectivity of imidazoacridinone C-1311 against FLT3-activated leukemia cells
PublicationDrugs targeting receptor tyrosine kinase FLT3 are of particular interest since activating FLT3-internal tandem duplication (ITD) mutations abundantly occur in fatal acute myeloid leukemias (AMLs). Imidazoacridinone C-1311, a DNA-reactive inhibitor of topoisomerase II, has been previously shown to be a potent and selective inhibitor of recombinant FLT3. Here, we expand those findings by studying its effect on leukemia cells with...