Adrian Tobiszewski - Publications - Bridge of Knowledge

Adrian Tobiszewski

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Year 2014

Molecular Recognition in Complexes of TRF Proteins with Telomeric DNA
Publication
- M. Wieczór
- A. Tobiszewski
- P. Wityk
- B. Tomiczek
- J. Czub
- PLOS ONE - Year 2014
Telomeres are specialized nucleoprotein assemblies that protect the ends of linear chromosomes. In humans and many other species, telomeres consist of tandem TTAGGG repeats bound by a protein complex known as shelterin that remodels telomeric DNA into a protective loop structure and regulates telomere homeostasis. Shelterin recognizes telomeric repeats through its two major components known as Telomere Repeat-Binding Factors, TRF1...

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