Year 2017

• Reactivation of seizure‐related changes to interictal spike shape and synchrony during postseizure sleep in patients

  Publication

  • M. R. Bower
  • M. T. Kucewicz
  • E. K. St. Louis
  • F. Meyer
  • W. R. Marsh
  • M. Stead
  • G. A. Worrell

  - EPILEPSIA - Year 2017

  OBJECTIVE: Local field potentials (LFPs) arise from synchronous activation of millions of neurons, producing seemingly consistent waveform shapes and relative synchrony across electrodes. Interictal spikes (IISs) are LFPs associated with epilepsy that are commonly used to guide surgical resection. Recently, changes in neuronal firing patterns observed in the minutes preceding seizure onset were found to be reactivated during postseizure...

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Year 2009

• EPILEPTIC BEHAVIOR WITH A DISTINGUISHED PREICTAL PERIOD IN A LARGE-SCALE NEURAL NETWORK MODEL

  Publication

  • J. Pyrzowski
  • J. Signerska-Rynkowska
  • M. Pyrzowski
  • B. Sulkowski

  - EPILEPSIA - Year 2009

  We present a neural network model capable of reproducing focal epileptic behavior. An important property of our model is the distinguished preictal state. This novel feature may shed light on the pathologi-cal mechanisms of seizure generation and, in perspective, help develop new therapeutic strategies to manage refractory partial epilepsy.

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