Maria Bieniaszewska - Publications - Bridge of Knowledge

Maria Bieniaszewska

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Year 2024

Dual-Activity Fluoroquinolone-Transportan 10 Conjugates offer alternative Leukemia therapy during Hematopoietic Cell Transplantation
Publication
- J. Lica
- M. Heldt
- M. Wieczór
- P. Chodnicki
- N. Ptaszyńska
- A. Łęgowska
- W. Brankiewicz
- K. Gucwa
- A. Stupak
- N. Maciejewska... and 8 others
- MOLECULAR PHARMACOLOGY - Year 2024
Hematopoietic cell transplantation (HCT) is often considered a last resort leukemia treatment, fraught with limited success due to microbial infections, a leading cause of mortality in leukemia patients. To address this critical issue, we explored a novel approach by synthesizing antileukemic agents containing antibacterial substances. This innovative strategy involves conjugating fluoroquinolone antibiotics, such as ciprofloxacin...

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