Abstract
In this review, we discuss recent studies relating to major features of adult MRL mouse biology that contribute to the regenerative responses seen. These include an increased inflammatory cell profile, a unique glycolytic metabolic state typically found during embryogenesis, and a cell cycle phenotype of DNA damage and G2/M arrest. These traits have been found in other mammalian and non-mammalian regenerative systems. How these physiological systems interact with each other and bring about regeneration is explored.
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- Category:
- Articles
- Type:
- artykuły w czasopismach
- Published in:
-
Gene Therapy and Regulation
no. 6,
pages 51 - 70,
ISSN: 1388-9532 - Language:
- English
- Publication year:
- 2011
- Bibliographic description:
- Arthur L. M., Sachadyn P., Gourevitch D., Heber-Katz E.: Cardinal regenerative features of the MRL mouse// Gene Therapy and Regulation -Vol. 6,iss. 1 (2011), s.51-70
- Verified by:
- Gdańsk University of Technology
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