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Convenient and Efficient Diastereoselective Preparation of Functionalized Z -Alkenyl Sulfides

Abstract

We have developed an efficient and convenient regio‐ and stereoselective reduction of the alkynyl sulfides with pinacolborane in the presence of copper(I) chloride to produce (Z)‐alkenyl sulfides in good and very good yields. The functionalized alkynyl sulfides are readily available based on the reaction of lithium acetylides with thiotosylates under mild conditions.

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DOI:
Digital Object Identifier (open in new tab) 10.1002/ejoc.201801181
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Copyright (2018 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim)

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Category:
Articles
Type:
artykuł w czasopiśmie wyróżnionym w JCR
Published in:
EUROPEAN JOURNAL OF ORGANIC CHEMISTRY no. 2018, pages 6333 - 6337,
ISSN: 1434-193X
Language:
English
Publication year:
2018
Bibliographic description:
Doroszuk J., Musiejuk M., Ponikiewski Ł., Witt D.: Convenient and Efficient Diastereoselective Preparation of Functionalized Z -Alkenyl Sulfides// EUROPEAN JOURNAL OF ORGANIC CHEMISTRY. -Vol. 2018, nr. 45 (2018), s.6333-6337
DOI:
Digital Object Identifier (open in new tab) 10.1002/ejoc.201801181
Verified by:
Gdańsk University of Technology

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