Search
Determination of the chemical structure of potential organic impurities occurring in drug substance opipramol
Abstract
The tricyclic antipsychotic and antidepressant drug opipramol (opipramole) was examined with regard to the chemical structure of its organic impurities. Impurities were isolated from the technical product by chromatographic methods and their chemical structures were established by 1H NMR, MS and FTIR and further confirmed by comparison with commercially available products or with products obtained by independent synthesis, and in one case additionally by X-ray structure analysis.
Citations
Authors (5)
-
-
Stanisław Magiełka
Cite as
Full text
full text is not available in portal
Details
- Category:
- Magazine publication
- Type:
- Magazine publication
- Published in:
-
PHARMAZIE
no. 65,
pages 239 - 244,
ISSN: 0031-7144 - Publication year:
- 2010
- DOI:
- Digital Object Identifier (open in new tab) doi: 10.1691/ph.2010.9309
- Verified by:
- No verification
seen 92 times
Recommended for you
Determination of the chemical structure of potencial organic impurities occuring in the drug substance opopramol
- E. Luboch,
- E. Wagner-Wysiecka,
- M. Jamrógiewicz
- + 2 authors
2010
Refining of Secondary Pb with Retention of Sn Using Al and Ca Additions
- D. Malecha,
- S. Małecki,
- P. Świec
- + 2 authors
2024
Forced degradation studies of ivabradine and in silico toxicology predictions for its new designated impurities
- M. Jamrógiewicz,
- P. Pikul,
- J. Nowakowska
- + 2 authors
2016