Search
Abstract
Biological drivers of empathy have been explored in an interdisciplinary manner for decades. Research that merges the psychological and genetic perspectives of empathy has recently gained interest, and more complex designs and analyses are needed. Empathy is a multidimensional construct that might be regarded both dispositionally (as a personality trait) and contextually (experienced and/or expressed in a particular relationship/situation). This study analyzed genetic variations associated with genes encoding oxytocin, arginine vasopressin, and receptors that regulate their secretion as predictors of the empathic dimensions of emotional (empathic concern and personal distress) and cognitive (perspective taking) dyadic factors of partners in heterosexual intimate relationships. Machine learning methods to capture both linear and nonlinear relationships between SNPs, RS1 and RS2 repeat polymorphisms and dimensions of empathy in couples were employed. A total of 442 individuals (221 couples) participated in this study. Empathy was measured by the Polish version of the Interpersonal Reactivity Index and the Interpersonal Reactivity Index for Couples. The MassARRAY® 4 instrument, which combines mass spectrometry with endpoint PCR, was used for genotyping all 14 genetic variations. Microsatellite fragment analysis was performed by denaturing polyacrylamide gel electrophoresis. The results confirmed the significance of certain genetic alterations linked to oxytocin, vasopressin, serotonin and estrogen for dispositional and dyadic empathy (mainly rs1884051, rs6311, RS1, rs4686302, and rs1042778) in couples. The effects were stronger for the prediction of emotional and dyadic empathy than for perspective taking. Separate analyses for women and men indicated different predictive effects of genes for empathy (for example, effects of rs53576 were indicated only in women), which are also experienced and expressed in couples. Different dimensions of empathy should be included when the genetic predictors of empathy are examined.
Citations
-
0
CrossRef
-
0
Web of Science
-
0
Scopus
Authors (3)
-
Maria Kaźmierczak
-
Magda Rybicka
Cite as
Full text
- Publication version
- Accepted or Published Version
- DOI:
- Digital Object Identifier (open in new tab) 10.1038/s41598-024-78857-7
- License
-
open in new tab
Keywords
Details
- Category:
- Articles
- Type:
- artykuły w czasopismach
- Published in:
-
Scientific Reports
no. 14,
ISSN: 2045-2322 - Language:
- English
- Publication year:
- 2024
- Bibliographic description:
- Kaźmierczak M., Rybicka M., Syty P.: Genetic variations as predictors of dispositional and dyadic empathy - a couple study// Scientific Reports -Vol. 14,iss. 1 (2024), s.27411-
- DOI:
- Digital Object Identifier (open in new tab) 10.1038/s41598-024-78857-7
- Sources of funding:
-
- IDUB
- Verified by:
- Gdańsk University of Technology
seen 7 times
Recommended for you
Forecasting energy consumption and carbon dioxide emission of Vietnam by prognostic models based on explainable machine learning and time series
- T. T. Le,
- P. Sharma,
- S. M. Osman
- + 5 authors