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Abstract
Fabrication of an appropriate skin scaffold needs to meet several standards related to the mechanical and biological properties. Fully natural/green scaffolds with acceptable biodegradability, biocompatibility, and physiological properties quite often suffer from poor mechanical properties. Therefore, for appropriate skin tissue engineering and to mimic the real functions, we need to use synthetic polymers and/or additives as complements to green polymers. Green nanocomposites (either nanoscale natural macromolecules or biopolymers containing nanoparticles) are a class of scaffolds with acceptable biomedical properties window (drug delivery and cardiac, nerve, bone, cartilage as well as skin tissue engineering), enabling one to achieve the required level of skin regeneration and wound healing. In this review, we have collected, summarized, screened, analyzed, and interpreted the properties of green nanocomposites used in skin tissue engineering and wound dressing. We particularly emphasize the mechanical and biological properties that skin cells need to meet when seeded on the scaffold. In this regard, the latest state of the art studies directed at fabrication of skin tissue and bionanocomposites as well as their mechanistic features are discussed, whereas some unspoken complexities and challenges for future developments are highlighted.
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Authors (11)
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Hanieh Shokrani
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Amirhossein Shokrani
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Maryam Jouyandeh
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Farzad Seidi
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Fatemeh Gholami
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Saptarshi Kar
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Muhammad Tajammal Munir
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Payam Zarrintaj
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Navid Rabiee
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Keywords
Details
- Category:
- Articles
- Type:
- artykuły w czasopismach
- Published in:
-
ACS Applied Bio Materials
no. 5,
pages 2107 - 2121,
ISSN: - Language:
- English
- Publication year:
- 2022
- Bibliographic description:
- Shokrani H., Shokrani A., Jouyandeh M., Seidi F., Gholami F., Kar S., Munir M. T., Kowalkowska-Zedler D., Zarrintaj P., Rabiee N., Saeb M.: Green Polymer Nanocomposites for Skin Tissue Engineering// ACS Applied Bio Materials -Vol. 5,iss. 5 (2022), s.2107-2121
- DOI:
- Digital Object Identifier (open in new tab) 10.1021/acsabm.2c00313
- Sources of funding:
-
- Free publication
- Verified by:
- Gdańsk University of Technology
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