Search
Invasive Assessment of the Myocardial Microcirculation during Beating Heart Coronary Artery Bypass Grafting
Abstract
Coronary artery bypass grafting may be associated with several cardiac complications, including ischemia, acute myocardial infarction, arrhythmias, or hemodynamic instability. Accumulating evidence suggests that well-developed coronary collateral circulation may protect against adverse effects, including myocardial ischemia. Assessment of myocardial microvascular perfusion is, therefore, of great clinical interest in beating heart surgery. In this paper, myocardial microvascular perfusion is continuously assessed on the beating heart using laser Doppler flowmetry in consecutive patients who underwent coronary artery bypass grafting procedures. No significant (p = 0.110) differences were found between the averaged perfusion signal (n = 42) at the baseline, during artery occlusion, or after reperfusion (732.4 ± 148.0 vs. 711.4 ± 144.1 vs. 737.0 ± 141.2, respectively). In contrast, significantly different (p < 0.001) mean perfusion signals (n = 12) were found (805.4 ± 200.1 vs. 577.2 ± 212.8 vs. 649.3 ± 220.8) in a subset of patients who presented with hemodynamic instability and myocardial ischemia. Additionally, a strong positive correlation between the plasma levels of high-sensitivity troponin I and perfusion decrease level after artery occlusion was found (r = 0.854, p < 0.001). This study argues that myocardial microvascular perfusion remains constant during coronary artery bypass grafting on the beating heart in advanced coronary artery disease. This phenomenon is most likely due to an extensive coronary collateral circulation.
Citations
-
2
CrossRef
-
0
Web of Science
-
3
Scopus
Cite as
Full text
- Publication version
- Accepted or Published Version
- DOI:
- Digital Object Identifier (open in new tab) 10.3390/jcm9030663
- License
-
open in new tab
Keywords
Details
- Category:
- Articles
- Type:
- artykuły w czasopismach
- Published in:
-
Journal of Clinical Medicine
no. 9,
ISSN: 2077-0383 - Language:
- English
- Publication year:
- 2020
- Bibliographic description:
- Kaszubowski M., Hellmann M.: Invasive Assessment of the Myocardial Microcirculation during Beating Heart Coronary Artery Bypass Grafting// Journal of Clinical Medicine -Vol. 9,iss. 3 (2020), s.663-
- DOI:
- Digital Object Identifier (open in new tab) 10.3390/jcm9030663
- Verified by:
- Gdańsk University of Technology
seen 109 times
Recommended for you
NADPH Oxidase Gene Polymorphism is Associated with Mortality and Cardiovascular Events in 7-Year Follow-Up
- M. Racis,
- W. Sobiczewski,
- A. Stanisławska-Sachadyn
- + 7 authors
A pilot study with flow mediated skin fluorescence: A novel device to assess microvascular endothelial function in coronary artery disease
- M. Tarnawska,
- K. Dorniak,
- M. F. Kaszubowski
- + 2 authors
Depression and anxiety in coronary artery bypass grafting patients
- J. Rymaszewska,
- A. Kiejna,
- T. Hadryś
The non-invasive evaluation of heart function in patients with an acute myocardial infarction: The role of impedance cardiography
- Ł. Lewicki,
- M. Fijałkowska,
- M. Karwowski
- + 5 authors