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Rapid and Green Separation of Mono- and Diesters of Monochloropropanediols by Ultrahigh Performance Supercritical Fluid Chromatography–Mass Spectrometry Using Neat Carbon Dioxide as a Mobile Phase
Abstract
This study demonstrates the effect of column selectivity and density of supercritical carbon dioxide (SC-CO2) on the separation of monochloropropanediol (MCPD) esters, known as food toxicants, using SC-CO2 without addition of cosolvent in ultrahigh performance supercritical fluid chromatography–mass spectrometry (UHPSFC-MS). This study shows that over 20 2-monochloropropanediol (2-MCPD) and 3-monochloropropanediol (3-MCPD) mono- and diesters are separated on a 2-picolylamine column in less than 12 min. The presence and position of a hydroxyl group in the structure, the number of unsaturated bonds, and the acyl chain length play a significant role in the separation of MCPD esters. The flow rate, backpressure, and column oven temperature, which affect the density of the mobile phase, were shown to have a substantial impact on retention, efficiency, and selectivity. The developed method was successfully applied for the determination of MCPD esters in refined oils and showed a close to excellent green analysis score using the Analytical Eco-Scale.
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Authors (7)
-
Firas Jumaah
- Lund University Centre for Analysis and Synthesis
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Sofia Essén
- Lund University Centre for Analysis and Synthesis
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Charlotta Turner Prof
- Lund University Centre for Analysis and Synthesis
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Margareta Sandahl
- Lund University Centre for Analysis and Synthesis
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Full text
- Publication version
- Accepted or Published Version
- License
- Copyright (2017 American Chemical Society)
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Details
- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
-
JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY
no. 65,
edition 37,
pages 8220 - 8228,
ISSN: 0021-8561 - Language:
- English
- Publication year:
- 2017
- Bibliographic description:
- Jumaah F., Jędrkiewicz R., Gromadzka J., Namieśnik J., Essén S., Turner C., Sandahl M.: Rapid and Green Separation of Mono- and Diesters of Monochloropropanediols by Ultrahigh Performance Supercritical Fluid Chromatography–Mass Spectrometry Using Neat Carbon Dioxide as a Mobile Phase// JOURNAL OF AGRICULTURAL AND FOOD CHEMISTRY. -Vol. 65, iss. 37 (2017), s.8220-8228
- DOI:
- Digital Object Identifier (open in new tab) 10.1021/acs.jafc.7b02857
- Verified by:
- Gdańsk University of Technology
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