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Synthesis, anticandidal activity of N3-(4-methoxyfumaroyl)-(S)-2,3-diaminopropanoic amide derivatives – Novel inhibitors of glucosamine-6-phosphate synthase
Abstract
Novel FMDP amiders 4-6 have been synthesized and tested against Candida strains. The anticandidal activity has been confined only to Candida albicans. Anticandidal activity of the tested amides has correlated with their inhibitory activity of glucosamine-6-phosphate synthase in cell free extract from Candida albicans.
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Authors (4)
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Magdalena Stolarska mgr inż.
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- Category:
- Articles
- Type:
- artykuł w czasopiśmie wyróżnionym w JCR
- Published in:
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EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY
no. 90,
pages 577 - 582,
ISSN: 0223-5234 - Language:
- English
- Publication year:
- 2015
- Bibliographic description:
- Pawlak D., Stolarska M., Wojciechowski M., Andruszkiewicz R.: Synthesis, anticandidal activity of N3-(4-methoxyfumaroyl)-(S)-2,3-diaminopropanoic amide derivatives – Novel inhibitors of glucosamine-6-phosphate synthase// EUROPEAN JOURNAL OF MEDICINAL CHEMISTRY. -Vol. 90, (2015), s.577-582
- DOI:
- Digital Object Identifier (open in new tab) 10.1016/j.ejmech.2014.12.007
- Verified by:
- Gdańsk University of Technology
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