Usefulness of chest perfusion computed tomography in the diagnosis of diabetic pulmonary microangiopathy

Renata Kalicka; Maciej Browarczyk; Seweryn Lipiński

doi:10.1016/j.bbe.2014.08.005

Usefulness of chest perfusion computed tomography in the diagnosis of diabetic pulmonary microangiopathy

Abstract

This paper presents the usefulness of perfusion computed tomography (pCT) in the diagnosis of diabetic pulmonary microangiopathy. Our previous works have shown that perfusion parameters are useful in the diagnosis of diabetic pulmonary microangiopathy. We are looking for such measurements and perfusion parameters that provide the most accurate diagnosis. Two types of comparison were made based on the results of clinical trials: non-diabetic vs. diabetic and diabetes without microangiopathy vs. diabetes with microangiopathy. Our studies have shown that PS (permeability surface) is only perfusion parameter statistically significant. In certain regions of interest logistic regression as a classifier produces very good results in diagnosing lung microangiopathy: sensitivity Sens = 89% and excellent specificity Spec = 100%. The results were obtained on the base of measurements taken from 23 subjects. These results were compared with results reported in the literature and based on diffusion capacity and spirometry measurements and modeling. None of the previous results was as good as those obtained using the PS and logistic regression for binary classification.

Citations

0

CrossRef
0

Web of Science
1

Scopus

Authors (3)

Renata Kalicka prof. dr hab. inż.
Maciej Browarczyk
Seweryn Lipiński
- Wydział Nauk Technicznych Katedra Elektrotechniki, Energetyki, Elektroniki i Automatyki

Cite as

Full text

full text is not available in portal

full content of the article see on external site open in new tab

Keywords

Details

Category:: Articles
Type:: artykuł w czasopiśmie wyróżnionym w JCR
Published in:: Biocybernetics and Biomedical Engineering no. 35, edition 1, pages 68 - 73,
ISSN: 0208-5216
Language:: English
Publication year:: 2015
Bibliographic description:: Kalicka R., Browarczyk M., Lipiński S.: Usefulness of chest perfusion computed tomography in the diagnosis of diabetic pulmonary microangiopathy// Biocybernetics and Biomedical Engineering. -Vol. 35, iss. 1 (2015), s.68-73
DOI:: Digital Object Identifier (open in new tab) 10.1016/j.bbe.2014.08.005
Verified by:: Gdańsk University of Technology