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• Antiproliferative, Antiangiogenic, and Antimetastatic Therapy Response by Mangiferin in a Syngeneic Immunocompetent Colorectal Cancer Mouse Model Involves Changes in Mitochondrial Energy Metabolism

  Publication

  • C. J. Rodriguez-Gonzalez
  • I. Hernández-Balmaseda
  • K. Declerck
  • C. Pérez-Novo
  • E. Logie
  • C. Theys
  • P. Jakubek
  • L. O. Quiñones-Maza
  • G. Dantas-Cassali
  • D. C. dos Reis... and 5 others

  - Frontiers in Pharmacology - Year 2021

  In spite of the current advances and achievements in cancer treatments, colorectal cancer (CRC) persists as one of the most prevalent and deadly tumor types in both men and women worldwide. Drug resistance, adverse side effects and high rate of angiogenesis, metastasis and tumor relapse remain one of the greatest challenges in long-term management of CRC and urges need for new leads of anticancer drugs. We demonstrate that CRC...

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