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Search results for: CHLOROQUINOXALINE

• Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: Their in silico assessment as potential ligands for N-protein of SARS-CoV-2

  Publication

  • S. Shahinshavali
  • K. A. Hossain
  • A. V. D. N. Kumar
  • A. G. Reddy
  • D. Kolli
  • A. Nakhi
  • M. V. B. Rao
  • M. Pal

  - TETRAHEDRON LETTERS - Year 2020

  In view of recent global pandemic the 3-alkynyl substituted 2-chloroquinoxaline framework has been explored as a potential template for the design of molecules targeting COVID-19. Initial in silico studies of representative compounds to assess their binding affinities via docking into the N-terminal RNA-binding domain (NTD) of N-protein of SARS-CoV-2 prompted further study of these molecules. Thus building of a small library of...

  Full text to download in external service

• Ultrasound assisted synthesis of 3-alkynyl substituted 2-chloroquinoxaline derivatives: their in silico assessment as potential ligands for N-protein of SARS-CoV-2

  Publication

  • S. Shahinshavali
  • A. Kumar
  • A. Reddy
  • D. Kolli
  • A. Nakhi
  • M. Rao
  • M. Pal
  • K. A. Hossain

  - TETRAHEDRON LETTERS - Year 2020

  Full text to download in external service