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Katedra Technologii Obiektów Pływających, Systemów Jakości i Materiałoznawstwa
Research Potential* badania optymalizacyjne nowych technologii oraz rodzajów rozwiązań konstrukcyjno - technologicznych konstrukcji kadłubów okrętowych * przemysłowe prototypy urządzeń i systemy zautomatyzowanej, sterowanej komputerowo diagnozy kształtu wielkogabarytowych konstrukcji płaskich * systemy dynamicznej kontroli jakości w trakcie produkcji kadłuba okrętowego * optymalizacja konstrukcji i technologii oraz budowa prototypów modułowej serii...
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Zespół ekoinżynierii i silników spalinowych
Research PotentialWysokosprawne, proekologiczne napędy i systemy konwersji energii
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Laboratorium Konstrukcji Oceanotechnicznych
Business OfferBadania mechaniczne, badania zmęczeniowe, badania metalograficzne, badania całych węzłów konstrukcyjnych, pomiary wytężenia rzeczywistych konstrukcji
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Search results for: MOLECULAR MOTORS
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Rotation Triggers Nucleotide-Independent Conformational Transition of the Empty β Subunit of F1-ATPase
PublicationF1-ATPase (F1) is the catalytic portion of ATP synthase, a rotary motor protein that couples proton gradients to ATP synthesis. Driven by a proton flux, the F1 asymmetric γ subunit undergoes a stepwise rotation inside the α3β3 headpiece and causes the β subunits’ binding sites to cycle between states of different affinity for nucleotides. These concerted transitions drive the synthesis of ATP from ADP and phosphate. Here, we study...
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Water-mediated long-range interactions between the internal vibrations of remote proteins
PublicationIt is generally acknowledged that the mobility of protein atoms and the mobility of water molecules in the solvation layer are connected. In this article, we answer the question whether a similar interdependence exists between the motions of atoms of proteins separated by the hydration layers of variable thickness. The system consisted of a kinesin catalytic domain and a tubulin dimer. It was studied using molecular dynamics simulations....
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The significance of the properties of water for the working cycle of the kinesin molecular motor
PublicationExplicit solvent molecular dynamics simulations were performed in this study to investigate and discuss several aspects of the influence of the properties of water on the working cycle of a molecular motor from the kinesin superfamily. The main objects of attention were: the binding of the neck linker and the association of the kinesin and the tubulin. The docking of the neck linker is considered a crucial event during the working...
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Properties of water in the region between a tubulin dimer and a single motor head of kinesin
PublicationA kinesin is a molecular motor that can perform movement on a microtubule track in a stepping-like manner. This motion is connected with processes of association and dissociation of kinesin and tubulin. Water is an important participant in these kinds of molecular interactions. This is why we have decided to investigate the dynamical and structural properties of water in the region between the kinesin catalytic domain and the tubulin...
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The importance of the shape of the protein–water interface of a kinesin motor domain for dynamics of the surface atoms of the protein
PublicationA single kinesin motor domain immersed in water has been investigated using molecular dynamics. It has been found that local properties of water in the solvation shell change along with the nature of the neighboring protein surface. However, a detailed analysis leads to the conclusion that the geometrical features of hydrogen bonds and overall structure of kinesin hydration water are not very different from bulk water. The local...