Search results for: NEUROPROTECTION
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Katedra Technologii Leków i Biochemii
Research PotentialRacjonalne projektowanie, synteza i badanie właściwości biologicznych nowych związków o działaniu przeciwnowotworowym lub przeciwgrzybowym
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Search results for: NEUROPROTECTION
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Neuroprotective Effect of SGLT2 Inhibitors
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The neuroprotective activity of new phenylalanine-based AMPA receptor antagonists
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Neuroprotective Effects of Cannabidiol in Hypoxic Ischemic Insult. The Therapeutic Window in Newborn Mice
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Phenylalanine-Based AMPA Receptor Antagonist as the Anticonvulsant Agent with Neuroprotective Activity—In Vitro and In Vivo Studies
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PTD4 Peptide Increases Neural Viability in an In Vitro Model of Acute Ischemic Stroke
PublicationIschemic stroke is a disturbance in cerebral blood flow caused by brain tissue ischemia and hypoxia. We optimized a multifactorial in vitro model of acute ischemic stroke using rat primary neural cultures. This model was exploited to investigate the pro-viable activity of cell-penetrating peptides: arginine-rich Tat(49–57)-NH2 (R49KKRRQRRR57-amide) and its less basic analogue, PTD4 (Y47ARAAARQARA57-amide). Our model included glucose...