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• Photosensitive and pH-dependent activity of pyrazine-functionalized carbazole derivative as promising antifungal and imaging agent

  Publication

  • A. Chylewska
  • A. Dąbrowska
  • S. Ramotowska
  • N. Maciejewska
  • M. Olszewski
  • M. Bagiński
  • M. Makowski

  - Scientific Reports - Year 2020

  Carbazole skeleton plays a significant role as a structural scaffold of many pharmacologically active compounds. Pyrazine-functionalized carbazole derivative was constructed by coupling 2-amino-5-bromo-3-methylaminepyrazine (ABMAP) into 3 and 6 positions of the carbazole ring. Multi-experimental methods were used, e.g., potentiometric, spectroscopic (ATR, UV, XRD powder,1H and13C NMR), electrochemical (cyclic voltammetry), and...

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