Search results for: REMDESIVIR
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Search results for: REMDESIVIR
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Remdesivir-based therapy improved recovery of patients with COVID-19 in the SARSTer multicentre, real-world study
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Remdesivir-based therapy improved recovery of patients with COVID-19 in the SARSTer multicentre, real-world study
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A 10-Year-old Girl With Late Acute Lymphoblastic Leukemia Recurrence Diagnosed With COVID-19 and Treated With Remdesivir
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Mechanism of reaction of RNA-dependent RNA polymerase from SARS-CoV-2
PublicationWe combine molecular dynamics, statistical mechanics, and hybrid quantum mechanics/molecular mechanics simulations to describe mechanistically the severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA-dependent RNA polymerase (RdRp). Our study analyzes the binding mode of both natural triphosphate substrates as well as remdesivir triphosphate (the active form of drug), which is bound preferentially over ATP by RdRp while...