Year 2022

• Collagen type II–hyaluronan interactions – the effect of proline hydroxylation: a molecular dynamics study

  Publication

  • P. Bełdowski
  • M. Przybyłek
  • D. Bełdowski
  • A. Dedinaite
  • A. Sionkowska
  • P. Cysewski
  • P. M. Claesson

  - Journal of Materials Chemistry B - Year 2022

  Hyaluronan–collagen composites have been employed in numerous biomedical applications. Understanding the interactions between hyaluronan and collagen is particularly important in the context of joint cartilage function and the treatment of joint diseases. Many factors affect the affinity of collagen for hyaluronan. One of the important factors is the ratio of 3- or 4-hydroxy proline to proline residues. This article presents...

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