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Flow cytometry analysis of DNA DSBs in telomerase positive and negative cell lines after treatment with TXT2 and TXT4
Description
Flow cytometry analysis of DNA DSBs in telomerase positive (A549, H460) and negative (NHBE2594, U2OS) cell lines after treatment with equitoxic concentrations of TXT2 and TXT4. MTX and DMSO were used as positive and negative controls, respectively.
DNA DSBs were detected using anti-phospho-Histone H2AX, Alexa 488 conjugate, a marker of double-strand DNA breaks.
Dataset file
Flow cytometry analysis of DNA DSB.zip
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File details
- License:
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CC BY-NC-SANon-commercial - Share-alike
Details
- Year of publication:
- 2022
- Verification date:
- 2023-03-24
- Dataset language:
- English
- Fields of science:
-
- chemical sciences (Natural sciences)
- DOI:
- DOI ID 10.34808/zfrv-bs73 open in new tab
- Funding:
- Verified by:
- Gdańsk University of Technology
Keywords
References
- publication Teloxantron inhibits the processivity of telomerase with preferential DNA damage on telomeres
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