Myelodysplastic syndrome, NOS - Male, 65 - Tissue image [11290630017293721] - Open Research Data - Bridge of Knowledge

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Myelodysplastic syndrome, NOS - Male, 65 - Tissue image [11290630017293721]

Description

This is the histopathological image of HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.

The detailed information about the patient, sample, and diagnosis are as follows:

Patient:

Age: 65

Clinical description: Patient with pancytopenia with increasing fatigue. As a result of the cytological smear of the bone marrow, signs of trilinear dysplasia were found

Gender: Male

Diagnosis:

Classification: ICD-O_3.2

Classification code: MYELODYSPLASTIC SYNDROMES

Diagnosis: Myelodysplastic syndrome, NOS

Result of the histopathological examination: Myelodysplastic syndrome with multilineage dysplasia (MDS-MDL) Marrow with cellularity of approx. 40% The topography of the main lines of hemopoiesis is slightly disturbed, the M: E ratio is 3: 2. Myeloid line MPO (+/-) / CD15 (+) with preserved segmental maturation (and with features of discrete dysgranulooesis). CD34 (+) / CD117 (+) blasts are diffuse and account for approx. 1% of the marrow cells CD71 (+) erythroid line in the form of poorly delimited islets with different cell composition, including some cells with uneven outline of the nuclei, some cells with megaloid regeneration features e-Cadherin (+) - features of dyserythropoiesis. CD61 (+) megakaryocytes slightly more numerous, with a slight irregularity in distribution. The dominant forms are small and medium ones with hypo- and hyperlobulation of the nucleis, single with micromegakaryocytes morphology. Bone trabeculae without significant pathological changes

Sample:

Material: FFPE

Collecting method: Bone marrow biopsy

Topography: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS

Organ: HEMATOPOIETIC AND RETICULOENDOTHELIAL SYSTEMS

Tissue: Bone marrow

Type of staining: positive/IHC

Staining: Gomori's Trichrome

Antibody: Not applicable

Technology:

Equipment: Pannoramic 250 3DHistech

Lens: 20x

Organization:

Source: Medical University Gdańsk

Dataset file

45a979ba-9b37-4119-80f8-2b582158e7d9
1.1 GB, S3 ETag , downloads: 26
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File details

License:
Creative Commons: by-nc-sa 4.0 open in new tab
CC BY-NC-SA
Non-commercial - Share-alike
Raw data:
Data contained in dataset was not processed.
Software:
CaseViewer 2.3

Details

Year of publication:
2021
Verification date:
2021-10-29
Creation date:
2021
Dataset language:
English
Fields of science:
  • medical sciences (Medical and Health Sciences )
DOI:
DOI ID 10.34808/ew5f-t745 open in new tab
Ethical papers:
NKBBN/421-306/2020
Verified by:
Medical University of Gdańsk

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