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Femtosecond Er-doped fiber laser source tunable from 872 to 1075 nm for two-photon vision studies in humans

Abstract

We report the development of a widely-tunable femtosecond fiber laser system and its application for two-photon vision studies. The source is based on an Er-doped fiber laser with spectral shift up to 2150 nm, followed by a second harmonic generation module to generate a frequency-doubled beam tunable from 872 to 1075 nm. The source delivers sub-230 fs pulses with nearly-constant duration over the entire tuning range, with output powers between 0.68–1.24 mW, which corresponds to a pulse energy of 13.2–24.1 pJ. Such pulse energy is sufficient for employing a system for measurements of two-photon scotopic spectral sensitivity of two-photon vision in humans. The laser parameters allow for very efficient and safe two-photon stimulation of the human visual system, as proved by a good separation between one- and two-photon thresholds for wavelengths below 950 nm, which we have confirmed for 3 healthy subjects.

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Authors (7)

  • Photo of  Dorota Stachowiak

    Dorota Stachowiak

    • Laser & Fiber Electronics Group, Faculty of Electronics, Photonics and Microsystems, Wrocław University of Science and Technology
  • Photo of  Jakub Bogusławski

    Jakub Bogusławski

    • International Centre for Translational Eye Research
  • Photo of  Zbigniew Łaszczych

    Zbigniew Łaszczych

    • Laser & Fiber Electronics Group, Faculty of Electronics, Photonics and Microsystems, Wrocław University of Science and Technology
  • Photo of Dr inż. Katarzyna Komar

    Katarzyna Komar Dr inż.

    • International Centre for Translational Eye Research
  • Photo of Prof. dr hab. Maciej Wojtkowski

    Maciej Wojtkowski Prof. dr hab.

    • Department of Physical Chemistry of Biological Systems, Institute of Physical Chemistry, Polish Academy of Sciences
  • Photo of dr hab. inż. Grzegorz Soboń

    Grzegorz Soboń dr hab. inż.

    • Laser & Fiber Electronics Group, Faculty of Electronics, Photonics and Microsystems, Wrocław University of Science and Technology

Keywords

Details

Category:
Articles
Type:
artykuły w czasopismach
Published in:
Biomedical Optics Express no. 13, pages 1899 - 1911,
ISSN: 2156-7085
Language:
English
Publication year:
2022
Bibliographic description:
Stachowiak D., Marzejon M., Bogusławski J., Łaszczych Z., Komar K., Wojtkowski M., Soboń G.: Femtosecond Er-doped fiber laser source tunable from 872 to 1075 nm for two-photon vision studies in humans// Biomedical Optics Express -Vol. 13,iss. 4 (2022), s.1899-1911
DOI:
Digital Object Identifier (open in new tab) 10.1364/boe.452609
Sources of funding:
  • Fundacja na rzecz Nauki Polskiej (First TEAM/2017-4/39, MAB/2019/12, TEAM TECH/2016-3/20); Narodowe Centrum Nauki (2016/23/B/ST2/00752)
Verified by:
Gdańsk University of Technology

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