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Abstract
There have been several attempts to find promising biomaterials for skin regeneration, among which polylysine (a homopolypeptide) has shown benefits in the regeneration and treatment of skin disorders. This class of biomaterials has shown exceptional abilities due to their macromolecular structure. Polylysine-based biomaterials can not only be used as tissue engineering scaffolds for skin regeneration, but also as drug carriers or even gene delivery vectors for the treatment of skin diseases. In addition, polylysine can play a preservative role in extending the lifetime of skin tissue by minimizing the appearance of photodamaged skin. Research on Polylysine is growing today, opening new scenarios that expand the potential of these biomaterials from traditional treatments to a new era of tissue regeneration. This review aims to address the basic concepts, recent trends, and prospects of polylysine-based biomaterials for skin regeneration. Undoubtedly, this class of biomaterials needs further evaluations and explorations, and many critical questions have yet to be answered.
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Authors (10)
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Payam Zarrintaj
- School of Chemical Engineering, Oklahoma State University, 420 Engineering North, Stillwater, OK, United States
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Sadegh Ghorbani
- Interdisciplinary Nanoscience Center (iNANO), Aarhus University, Aarhus, Denmark
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Mahmood Barani
- Medical Mycology and Bacteriology Research Center, Kerman University of Medical Sciences, Kerman, Iran
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Narendra Pal Singh Chauhan
- Department of Chemistry, Faculty of Science, Bhupal Nobles' University, Udaipur, Rajasthan, India
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Mohsen Khodadadi Yazdi
- School of Chemistry, College of Science, University of Tehran, Tehran, Iran
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Joshua D. Ramsey
- School of Chemical Engineering, Oklahoma State University, 420 Engineering North, Stillwater, OK, United States
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Michael R. Hamblin
- Wellman Center for Photomedicine, Massachusetts General Hospital, Boston, MA, United States
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Masoud Mozafari
- Lunenfeld-Tanenbaum Research Institute, Mount Sinai Hospital, University of Toronto, Toronto, ON, Canada
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Ebrahim Mostafavi
- Stanford Cardiovascular Institute, Stanford University School of Medicine, Stanford, CA, United States
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Full text
- Publication version
- Accepted or Published Version
- DOI:
- Digital Object Identifier (open in new tab) 10.1002/btm2.10261
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- Category:
- Articles
- Type:
- artykuły w czasopismach
- Published in:
-
Bioengineering & Translational Medicine
no. 7,
ISSN: - Language:
- English
- Publication year:
- 2022
- Bibliographic description:
- Zarrintaj P., Ghorbani S., Barani M., Singh Chauhan N. P., Khodadadi Yazdi M., Saeb M., Ramsey J. D., Hamblin M. R., Mozafari M., Mostafavi E.: Polylysine for Skin Regeneration: A Review of Recent Advances and Perspectives// Bioengineering & Translational Medicine -Vol. 7,iss. 1 (2022), s.e10261-
- DOI:
- Digital Object Identifier (open in new tab) 10.1002/btm2.10261
- Verified by:
- Gdańsk University of Technology
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