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Search results for: ONEURODEGENERATION

  • The Unfolded Protein Response: A Double-Edged Sword for Brain Health

    Publication
    • M. Gebert
    • J. Sławski
    • L. Kalinowski
    • J. F. Collawn
    • R. Bartoszewski

    - Antioxidants - Year 2023

    Efficient brain function requires as much as 20% of the total oxygen intake to support normal neuronal cell function. This level of oxygen usage, however, leads to the generation of free radicals, and thus can lead to oxidative stress and potentially to age-related cognitive decay and even neurodegenerative diseases. The regulation of this system requires a complex monitoring network to maintain proper oxygen homeostasis. Furthermore,...

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