Search results for: CRYSTAL DEHYDRATION

• Dehydration converts DsbG crystal diffraction from low to high resolution

  Publication

  • B. Heras
  • M. A. Edeling
  • K. A. Byriel
  • A. Jones
  • S. Raina
  • J. L. Martin

  - STRUCTURE - Year 2003

  Diffraction quality crystals are essential for crystallographic studies of protein structure, and the production of poorly diffracting crystals is often regarded as a dead end in the process. Here we show a dramatic improvement of poorly diffracting DsbG crystals allowing high-resolution diffraction data measurement. Before dehydration, the crystals are fragile and the diffraction pattern is streaky, extending to 10 Å resolution....

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• Oxolane Ammonium Salts (Muscarine-Like)—Synthesis and Microbiological Activity

  Publication

  • P. Bogdanowicz
  • J. Madaj
  • P. Szweda
  • A. Sikorski
  • J. Samaszko-Fiertek
  • B. Dmochowska

  - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2024

  Commercially available 2-deoxy-D-ribose was used to synthesize the appropriate oxolane derivative—(2R,3S)-2-(hydroxymethyl)oxolan-3-ol—by reduction and dehydration/cyclization in an acidic aqueous solution. Its monotosyl derivative, as a result of the quaternization reaction, allowed us to obtain eight new muscarine-type derivatives containing a quaternary nitrogen atom and a hydroxyl group linked to the oxolane ring. Their structure...

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