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Search results for: MELANOMA
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Melanoma Management
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MELANOMA RESEARCH
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Transplantable Melanomas in Hamsters and Gerbils as Models for Human Melanoma. Sensitization in Melanoma Radiotherapy—From Animal Models to Clinical Trials
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The role of melanin pigment in melanoma
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Vitamin D signaling and melanoma: role of vitamin D and its receptors in melanoma progression and management
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Proteomic profile of melanoma cell‐derived small extracellular vesicles in patients’ plasma: a potential correlate of melanoma progression
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Intelligent system supporting diagnosis of malignant melanoma
PublicationMalignant melanomas are the most deadly type of skin cancers. Early diagnosis is a key for successful treatment and survival. The paper presents the system for supporting the process of diagnosis of skin lesions in order to detect a malignant melanoma. The paper describes the development process of an intel-ligent system purposed for the diagnosis of malignant melanoma. Presented sys-tem can be used as a decision support system...
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New vitamin D analogs as potential therapeutics in melanoma
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Common variants of DNA repair genes and malignant melanoma
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Liquid Biopsy in Melanoma: Significance in Diagnostics, Prediction and Treatment Monitoring
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The assessment of students’ knowledge regarding melanoma and sun-protection habits
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XPD Common Variants and their Association with Melanoma and Breast Cancer Risk
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Proteomic Analysis of Proton Beam Irradiated Human Melanoma Cells
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ELECTROCHEMOTHERAPY COMBINED WITH STANDARD AND CO2 LASER SURGERIES IN CANINE ORAL MELANOMA
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On the role of classical and novel forms of vitamin D in melanoma progression and management
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MC1R common variants, CDKN2A and their association with melanoma and breast cancer risk
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Novel therapeutic compound acridine–retrotuftsin action on biological forms of melanoma and neuroblastoma
PublicationPURPOSE: As a continuation of our search for anticancer agents, we have synthesized a new acridine-retrotuftsin analog HClx9-[Arg(NO2)-Pro-Lys-Thr-OCH3]-1-nitroacridine (named ART) and have evaluated its activity against melanoma and neuroblastoma lines. Both tumors develop from cells (melanocytes, neurons) of neuroectodermal origin, and both are tumors with high heterogeneity and unsatisfactory susceptibility to chemotherapies....
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Fluorescence Imaging Using Methylene Blue Sentinel Lymph Node Biopsy in Melanoma
PublicationIntroduction: Fluorescence imaging of sentinel node biopsy in melanoma is a novel method. Both indocyanine green (ICG) and methylene blue (MB) have fl uorescent properties. The aim of this study was to present, for the fi rst time in a clinical series of patients, the possible usage of MB as a fl uorescent dye for sentinel node biopsy during surgery for melanoma. Material and methods: Twenty patients with...
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Melanoma skin cancer detection using mask-RCNN with modified GRU model
PublicationIntroduction: Melanoma Skin Cancer (MSC) is a type of cancer in the human body; therefore, early disease diagnosis is essential for reducing the mortality rate. However, dermoscopic image analysis poses challenges due to factors such as color illumination, light reflections, and the varying sizes and shapes of lesions. To overcome these challenges, an automated framework is proposed in this manuscript. Methods: Initially, dermoscopic...
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Cytotoxic effect on human melanoma cell lines and tyrosinase inhibition of Hottonia palustris
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Anticancer properties of ester derivatives of betulin in human metastatic melanoma cells (Me-45)
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The effects of p53 gene inactivation on mutant proteome expression in a human melanoma cell model
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Apoptosis induction in C32 human melanoma cells by Jasione montana and its main phytoconstituents
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Graphene-encapsulated iron nanoparticles as a non-viral vector for gene delivery into melanoma cells
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An Insight into the Proteome of Uveal Melanoma-Derived Ectosomes Reveals the Presence of Potentially Useful Biomarkers
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Similarities and Differences in the Protein Composition of Cutaneous Melanoma Cells and Their Exosomes Identified by Mass Spectrometry
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Polymer-free cubosomes for simultaneous bioimaging and photodynamic action of photosensitizers in melanoma skin cancer cells
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Using Flavonoid Substitution Status to Predict Anticancer Effects in Human Melanoma Cancers: An In Vitro Study
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Antitumor Effects of Vitamin D Analogs on Hamster and Mouse Melanoma Cell Lines in Relation to Melanin Pigmentation
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In Vitro Anticancer Potential of Jasione montana and Its Main Components against Human Amelanotic Melanoma Cells
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Mass Spectrometry-Based Proteomic Characterization of Cutaneous Melanoma Ectosomes Reveals the Presence of Cancer-Related Molecules
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DEEP CONVOLUTIONAL NEURAL NETWORKS AS A DECISION SUPPORT TOOL IN MEDICAL PROBLEMS – MALIGNANT MELANOMA CASE STUDY
PublicationThe paper presents utilization of one of the latest tool from the group of Machine learning techniques, namely Deep Convolutional Neural Networks (CNN), in process of decision making in selected medical problems. After the survey of the most successful applications of CNN in solving medical problems, the paper focuses on the very difficult problem of automatic analyses of the skin lesions. The authors propose the CNN structure...
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DIAGNOSIS OF MALIGNANT MELANOMA BY NEURAL NETWORK ENSEMBLE-BASED SYSTEM UTILISING HAND-CRAFTED SKIN LESION FEATURES
PublicationMalignant melanomas are the most deadly type of skin cancer but detected early have high chances for successful treatment. In the last twenty years, the interest of automated melanoma recognition detection and classification dynamically increased partially because of public datasets appearing with dermatoscopic images of skin lesions. Automated computer-aided skin cancer detection in dermatoscopic images is a very challenging task...
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Low prevalence of CDKN2A/ARF mutations among early-onset cancers of breast, pancreas and malignant melanoma in Poland
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Antiproliferative Activity of Double Point Modified Analogs of 1,25-Dihydroxyvitamin D2 Against Human Malignant Melanoma Cell Lines
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Photo-conversion of two epimers (20R and 20S) of pregna-5,7-diene-3β, 17α, 20-triol and their bioactivity in melanoma cells
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Synthesis and photochemical transformation of 3β,21-dihydroxypregna-5,7-dien-20-one to novel secosteroids that show anti-melanoma activity
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Complete tumour regressions induced by vaccination with IL-12 gene-transduced tumour cells in combination with IL-15 in a melanoma model in mice
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Designing a High-sensitivity Microscale Triple-band Biosensor based on Terahertz MTMs to provide a perfect absorber for Non-Melanoma Skin Cancer diagnostic
PublicationNon-melanoma skin cancer (NMSC) is among the most prevalent forms of cancer originating in the top layer of the skin, with basal cell carcinoma (BCC) and squamous cell carcinoma (SCC) being its primary categories. While both types are highly treatable, the success of treatment hinges on early diagnosis. Early-stage NMSC detection can be achieved through clinical examination, typically involving visual inspection. An alternative,...
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Antiproliferative activity of side-chain truncated vitamin D analogs (PRI-1203 and PRI-1204) against human malignant melanoma cell lines
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Pigment Cell & Melanoma Research
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Designing a high-sensitivity dual-band nano-biosensor based on petahertz MTMs to provide a perfect absorber for early-stage non-melanoma skin cancer diagnostic
PublicationThe purpose of this study is development of a novel high-performance low-Petahertz (PHz) biosensor for non-melanoma skin cancer (NMSC) diagnosis. The presented device is designed to work within a microwave imaging regime, which is a promising alternative to conventional diagnostic methods such as visual examination, dermoscopy, and biopsy. The suggested biosensor incorporates a dual-band perfect absorber (operating bands at 0.909...
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Pulse-Modulated Radio-Frequency Alternating-Current-Driven Atmospheric-Pressure Glow Discharge for Continuous-Flow Synthesis of Silver Nanoparticles and Evaluation of Their Cytotoxicity toward Human Melanoma Cells
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L-tyrosine and L-dihydroxyphenylalanine as hormone-like regulators of melanocyte functions
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Acral melanoma - Male, 63 - Tissue image [9200729571536371]
Open Research DataThis is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Acral melanoma - Male, 63 - Tissue image [9200729571534041]
Open Research DataThis is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Acral melanoma - Male, 63 - Tissue image [9200729571538591]
Open Research DataThis is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Acral melanoma - Male, 63 - Tissue image [9200729571532701]
Open Research DataThis is the histopathological image of SKIN tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Melanoma, metastatic - Female, 57 - Tissue image [9140730014152241]
Open Research DataThis is the histopathological image of LIVER AND INTRAHEPATIC BILE DUCTS tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.
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Melanoma, metastatic - Male, 69 - Tissue image [10040729541214881]
Open Research DataThis is the histopathological image of LYMPH NODES tissue sample obtained in Medical University Gdańsk and deposited in ZMDL-GUMED. The sample image was taken using: Pannoramic 250 3DHistech slide scanner (20x magnification) and saved to DICOM format.