Search results for: UDP-GLUCURONYLTRANSFERASES

• The II phase metabolism of endogenous and exogenous compounds, including antitumor chemotherapeutics

  Publication

  • Z. Mazerska
  • A. Mróz
  • A. Bejrowska
  • B. Borowa-Mazgaj
  • A. Potęga
  • E. Augustin

  - Year 2014

  The II phase metabolism, it is a set of metabolism and excretion pathways of endogenous as well as exogenous compounds including xenobiotics. UDP-glucuronyltransferases (UGTs; EC 2.4.1.17) are the most crucial representatives of II phase enzymes, which are responsible for the transformation of bilirubine and bile acids, steroids and thyroid hormones and lipids. Exogenous compounds, including drugs, carcinogens, environmental pollutants...