Search results for: diastereoselectivity

• Diastereoselective Synthesis of Z‐Alkenyl Disulfides from α‐Thiophosphorylated Ketones and Thiosulfonates

  Publication

  • M. Musiejuk
  • J. Doroszuk
  • B. Jędrzejewski
  • G. Ortiz Nieto
  • M. S. Marin Navarro
  • D. Witt

  - ADVANCED SYNTHESIS & CATALYSIS - Year 2020

  We developed a simple and efficient method for the synthesis of functionalized unsymmetrical Z‐alkenyl disulfides under mild conditions in moderate to good yields. The designed method is based on the reaction of α‐thiophosphorylated carbonyl compounds with thiotosylates in the presence of a base. The developed method allows the preparation of unsymmetrical Z‐alkenyl disulfides bearing additional hydroxy, carboxy, or ester functionalities

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