Search results for: EPIGENETIC DRUGS

• Disposition of Drugs of Abuse and Their Metabolites in Wastewater as a Method of the Estimation of Drug Consumption

  Publication

  • E. Daghir
  • M. J.

  - Current Drug Metabolism - Year 2010

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• Methods for Elucidation of DNA-Anticancer Drug Interactions and Their Applications in the Development of New Drugs

  Publication

  • M. Misiak
  • F. Mantegazza
  • G. Beretta

  - CURRENT PHARMACEUTICAL DESIGN - Year 2016

  DNA damaging agents including anthracyclines, camptothecins and platinum drugs are among most frequently used drugs in the chemotherapeutic routine. Due to their relatively low selectivity for cancer cells, administration is associated with adverse side effects, whereas the inherent genotoxicity of these drugs is associated with risk of developing secondary cancers. Development of new drugs, which could be spared of these drawbacks...

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• The role of epigenetics in regeneration

  Publication

  • J. Podolak-Popinigis
  • B. Górnikiewicz

  - Year 2013

  Complex changes in chromatin structure and at the transcriptional level occur from the creation of a single parental gamete throughout fertilization, embryo development and the life of an adult organism. Epigenetic changes, such as methylation and hydroxymethylation of DNA or histone methylation and acetylation, are an important part of these processes. Epigenetic regulation has an essential influence on gene expression level. DNA...

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• Genetic and Epigenetic Aspects of Atopic Dermatitis

  Publication

  • B. Nedoszytko
  • E. Reszka
  • D. Gutowska-Owsiak
  • M. Trzeciak
  • M. Lange
  • J. Jarczak
  • M. Niedoszytko
  • E. Jablonska
  • J. Romantowski
  • D. Strapagiel... and 6 others

  - INTERNATIONAL JOURNAL OF MOLECULAR SCIENCES - Year 2020

  Atopic dermatitis is a heterogeneous disease, in which the pathogenesis is associated with mutations in genes encoding epidermal structural proteins, barrier enzymes, and their inhibitors; the role of genes regulating innate and adaptive immune responses and environmental factors inducing the disease is also noted. Recent studies point to the key role of epigenetic changes in the development of the disease. Epigenetic modifications...

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• Genetics & Epigenetics

  Journals

  ISSN: 1179-237X

• Epigenetics & Chromatin

  Journals

  ISSN: 1756-8935

• EPIGENETICS-US

  Journals

  ISSN: 1559-2294 , eISSN: 1559-2308

• Epigenetics Insights

  Journals

  ISSN: 2516-8657

• Environmental Epigenetics

  Journals

  ISSN: 2058-5888

• Optical properties of the chemotherapy drugs used in the central nervous system lymphoma therapy: monitoring drug delivery

  Publication

  • T. Myllylä
  • A. P. Popov
  • Ł. Surażyński
  • J. Oinas
  • O. Bibikova
  • A. Bykov
  • M. Wróbel
  • M. Gnyba
  • M. Szczerska
  • I. Meglinski
  • O. Kuittinen

  - Year 2015

  Our aim is to optically monitor the delivery of the chemotherapy drugs for brain tumours, particularly used in the central nervous system (CNS) lymphoma therapy. In vivo monitoring would help to optimize the treatment and avoiding unnecessary medications. Moreover, it would be beneficial to be able to measure which of the multi-regimen drugs actually do penetrate and how well into the brain tissue. There exist several potential...

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