Search results for: aureofacin

• Ipertrofan Revisited—The Proposal of the Complete Stereochemistry of Mepartricin A and B

  Publication

  • P. Szczeblewski
  • W. Andrałojć
  • J. Polit
  • A. Żabka
  • K. Winnicki
  • T. Laskowski

  - MOLECULES - Year 2021

  Being a methyl ester of partricin, the mepartricin complex is the active substance of a drug called Ipertrofan (Tricandil), which was proven to be useful in treatment of benign prostatic hyperplasia and chronic nonbacterial prostatitis/chronic pelvic pain syndrome. Nevertheless, no direct structural evidence on the stereochemistry of its components has been presented to date. In this contribution, we have conducted detailed, NMR-driven...

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