Search results for: carnosinase

• Human carnosinases: A brief history, medicinal relevance, and in silico analyses

  Publication

  • K. Chmielewska
  • S. Vittorio
  • S. Gervasoni
  • K. Dzierzbicka
  • I. Inkielewicz-Stępniak
  • G. Vistoli

  - DRUG DISCOVERY TODAY - Year 2024

  Carnosine, an endogenous dipeptide, has been found to have a plethora of medicinal properties, such as antioxidant, antiageing, and chelating effects, but with one downside: a short half-life. Carnosinases and two hydrolytic enzymes, which remain enigmatic, are responsible for these features. Hence, here we emphasize why research is valuable for better understanding crucial concepts like ageing, neurodegradation, and cancerogenesis,...

  Full text available to download

• Therapeutic Potential of Carnosine and Its Derivatives in the Treatment of Human Diseases

  Publication

  • K. Chmielewska
  • K. Dzierzbicka
  • I. Inkielewicz-Stępniak
  • M. Przybyłowska

  - CHEMICAL RESEARCH IN TOXICOLOGY - Year 2020

  Despite significant progress in the pathogenesis, diagnosis, treatment, and prevention of cancer and neurodegenerative diseases, their occurrence and mortality are still high around theworld. The resistance of cancer cells to the drugs remains a significant problem in oncology today,while in the case of neuro-degenerative diseases, therapies reversing the process are still yet to be found. Furthermore, it is important to seek new...

  Full text available to download

• Anserine and carnosine supplementation in the elderly: Effects on cognitive functioning and physical capacity

  Publication

  • D. Szcześniak
  • S. Budzeń
  • W. Kopeć
  • J. Rymaszewska

  - Archives of Gerontology and Geriatrics - Year 2014

  Full text to download in external service