Year 2016

• Improved cytotoxicity and preserved level of cell death induced in colon cancer cells by doxorubicin after its conjugation with iron-oxide magnetic nanoparticles

  Publication

  • E. Augustin
  • B. Czubek
  • A. M. Nowicka
  • A. Kowalczyk
  • Z. Stojek
  • Z. Mazerska

  - TOXICOLOGY IN VITRO - Year 2016

  A promising strategy for overcoming the problem of limited efficacy in antitumor drug delivery and in drug release is the use of a nanoparticle-conjugated drug. Doxorubicin (Dox) anticancer chemotherapeutics has been widely studied in this respect, because of severe cardiotoxic side effects. Here, we investigated the cytotoxic effects, the uptake process, the changes in cell cycle progression and the cell death processes in the...

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